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Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

Hair loss in women can be slowed with treatment, but more research needed for better solutions.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Finasteride safely lowers DHT levels without affecting testosterone.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

3α, 17β-androstanediol-glucuronide is not a useful marker for androgen excess but may help monitor certain treatments.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.

Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.

Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Pumpkin seed products may help improve prostate and bladder health by blocking certain enzymes and hormone receptors.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.