The Nominal Trial: Clinical Efficacy, Cosmetic Acceptability, and Local Tolerability of Topical 5% Minoxidil Lotion Without Propylene Glycol: A 6-Month, Multicentre, Real-Life, Prospective, Assessor-Blinded Study in 196 Subjects With Hair Loss

January 2021 in “ Medical research archives ”

Laura Alessi, Maria Stella Aloisi, Valentina Amadu, Alex Arena, Ylenia Balice, Stefania Bano, Stefania Barruscotti, Annunziata Bartolotta, Silvia Bondino, Arianna Corsini, Di Nunno, Stefania Farina, Paola Nappa, Luigi Pisano, Fabrizio Presta, Nicolo Rivetti, Elena Saccani, Marco Tomassini, Sonia Torti, Fabrizio Vaira, Giovanni Zanframundo, Mario Puviani, Klause Eisendle, Massimo Milani

minoxidil 5% minoxidil lotion androgenic alopecia female androgenic alopecia topical treatment propylene glycol Rogaine

TLDR The 5% minoxidil lotion without propylene glycol is effective, well-tolerated, and cosmetically acceptable for hair loss.

The NOMINAL trial assessed a 5% minoxidil lotion without propylene glycol in 196 subjects with androgenic alopecia and female androgenic alopecia over 6 months. Conducted in 22 Italian dermatology clinics, 74% of subjects showed good or very good clinical response by week 24, confirmed by an assessor-blinded evaluation in 60 subjects. Cosmetic acceptability was high, with mean scores below 2, and 94% rated global tolerability as very good. No severe adverse effects were reported, indicating the lotion was well-tolerated and effective in real-life conditions.

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research The Nominal Trial: Clinical Efficacy, Cosmetic Acceptability, and Local Tolerability of Topical 5% Minoxidil Lotion Without Propylene Glycol: A 6-Month, Multicentre, Real-Life, Prospective, Assessor-Blinded Study in 196 Subjects With Hair Loss

January 2021 in “Medical research archives”

The 5% minoxidil lotion without propylene glycol is effective, well-tolerated, and cosmetically acceptable for hair loss.

research Clinical Efficacy, Cosmetic Acceptability, and Local Tolerability of a New Formulation of Topical 5% Minoxidil Without Propylene Glycol: A 6-Month, Multicentre, Real-Life, Prospective, Assessor-Blinded Study in 196 Subjects with Hair Loss. The NOMINAL Trial

January 2021 in “Journal of clinical & experimental dermatology research”

The new 5% minoxidil formulation without propylene glycol effectively promotes hair growth with fewer side effects and better user satisfaction.

The Nominal Trial: Clinical Efficacy, Cosmetic Acceptability, and Local Tolerability of Topical 5% Minoxidil Lotion Without Propylene Glycol: A 6-Month, Multicentre, Real-Life, Prospective, Assessor-Blinded Study in 196 Subjects With Hair Loss

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research The Nominal Trial: Clinical Efficacy, Cosmetic Acceptability, and Local Tolerability of Topical 5% Minoxidil Lotion Without Propylene Glycol: A 6-Month, Multicentre, Real-Life, Prospective, Assessor-Blinded Study in 196 Subjects With Hair Loss

research Clinical Efficacy, Cosmetic Acceptability, and Local Tolerability of a New Formulation of Topical 5% Minoxidil Without Propylene Glycol: A 6-Month, Multicentre, Real-Life, Prospective, Assessor-Blinded Study in 196 Subjects with Hair Loss. The NOMINAL Trial