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This study discusses the challenges in translating organoid models from laboratory settings to clinical and commercial applications, emphasizing the need for engineering approaches like environmental recapitulation and matrix engineering to bridge this gap.

This study explored the mechanism of Shaoyao Gancao decoction in treating alopecia areata and found that it may be closely related to the PI3K/AKT signaling pathway.

In this laboratory study, researchers observed that mouse vascular endothelial cells exhibit dynamic changes after exposure to ionizing radiation, including a transient endothelial subpopulation that facilitates vascular-epidermal communication and skin repair, with shifting roles in angiogenesis and immune surveillance over time.

This study used single-cell RNA sequencing to analyze 26,573 cells from the scapular skin of yaks, identifying 11 major cell types and providing insights into the diversity and morphogenesis of hair follicle cell types through detailed maps of DP cells and dermal fibroblasts.

In this study, researchers used single-cell RNA sequencing to identify cell types and molecular differences in subcutaneous adipose tissue from various anatomical sites, suggesting that certain subpopulations of human adipose stem cells might improve the treatment of chronic refractory wounds.

This study reported that tail tip lesions in dairy cows include granulation tissue, purulent-necrotizing inflammation, and hyperkeratosis, potentially caused by ischemia.

This study identified the dermal sheath as a driver of hair follicle regression through muscle contraction, essential for reuniting niches and stem cells to regenerate tissue structure during homeostasis.

This manuscript explores the development and future potential of injectable biomimetic gels in biomedical applications, highlighting their promise in wound healing and tissue regeneration, while also acknowledging challenges like mechanical durability and scalable production still persist.

This review highlights silk fibroin and its nanocomposites as promising materials for wound healing, addressing challenges in chronic wound treatment, especially in developing countries, and examines the obstacles in bringing silk-based products to market.

This review outlines recent advances in stem cell and tissue engineering technologies in regenerative medicine and wildlife conservation, reporting no new clinical results.

This study found that the tetracycline-regulated transcription system effectively controls conditional gene expression in the mouse epidermis, allowing suppression and activation of specific genes with doxycycline.

This review describes adipose tissue-derived therapies as promising for osteoarthritis, with potential to repair cartilage, reduce inflammation, and enhance joint function, highlighting advancements and their potential future applications.

This review highlights the promising biomedical applications of marine-derived polysaccharides, proteins, and peptides, particularly in drug delivery and wound healing. It discusses their potential as biomaterials in creating nanocarriers, hydrogels, and more, alongside fabrication strategies, regulatory challenges, and sustainability considerations.

This review discusses surgical approaches and new advancements in sternum reconstruction, emphasizing innovative techniques and materials, but reports no new clinical results.

This study explores the transformative role of tissue engineering in cosmetics, highlighting innovations like lab-grown skin and personalized grafts that enhance product efficacy, offer ethical alternatives to animal testing, and address aesthetic issues such as scarring and aging.

This review outlines the design and engineering of multifunctional hydrogels, emphasizing their evolving biomedical applications, notably in controlled drug delivery, tissue support, and disease management, and discusses their potential for clinical translation.

This review explores the potential of regenerative cosmetics, specifically engineered skin tissues, for rejuvenating aging skin, healing wounds, and restoring hair, offering promising alternatives to traditional dermocosmetic treatments by promoting collagen production, reducing wrinkles, and regenerating hair follicles.

This review highlights the diverse roles of melanocytes in pigmentation, immunity, and hearing among other functions, their involvement in disorders, and their emerging potential in regenerative medicine, including applications in disease modeling and therapy development using advanced technologies.

This review discusses the potential of microneedles to enhance transdermal drug delivery by expanding the range of deliverable drugs, highlighting fabrication methods, material choices, and applications, but notes existing challenges with sustained delivery, cost-effectiveness, and large-scale production.

This review article highlights recent advances in microneedle technology for wound healing and tissue regeneration, discussing various cargo types, structural designs, and fabrication methods, and suggesting guidelines for designing microneedle systems tailored to specific applications.

In this study, an injectable self-healing bioactive nanoglass hydrogel showed promise for repairing normal and MRSA-infected skin wounds by inhibiting bacterial growth and reducing inflammation.

In this study, researchers found that coordinated intercellular Ca2+ signaling among basal stem cells in mice is crucial for cell cycle progression and tissue-wide communication during epidermal regeneration.

This review highlights advancements in electrospun nanofibers, focusing on their potential applications in biomedical technologies, chemical and biological sensing, and energy harvesting within IoT devices.

In laboratory and artificial skin model experiments, this study found that plant-derived PDRN from Korean ginseng effectively promoted skin cell regeneration and strengthened the skin barrier, suggesting a sustainable alternative to animal-derived PDRN.

This review explores the potential diagnostic and therapeutic applications of extracellular vesicles in treating various skin conditions but reports no new clinical study results.

This paper reviews the molecular mechanisms involved in hair follicle development, highlighting their potential impact on human health and well-being, and discusses advancements in treating hair loss, enhancing wound healing, and developing cosmetic treatments.

This study found that injectable gelatin/metal/tea polyphenol double nanonetworks significantly accelerated wound healing in diabetic wounds by enhancing cell migration and providing anti-inflammatory and antioxidant properties, without detectable cytotoxicity in tests.

This review examines how mathematical modeling of the MAPK pathway, enhanced by single-cell proteomic data, improves understanding of regulatory mechanisms, predicts system behavior, and guides experimental research, emphasizing recent developments in modeling and inference.

This review highlights recent advances in ultrasound-based radiomics and radiogenomics for ovarian cancer, suggesting these techniques improve diagnostic accuracy and patient-specific treatment strategies, despite ongoing challenges with standardization and model interpretability.

In this study, researchers investigated a regulatory network in cashmere goat embryos and found that fibroblast growth factor 10, alongside non-coding RNAs, significantly influences hair follicle cell proliferation, offering insights into the biology of hair follicles in cashmere goats.