Epidermal Stem Cells Manipulated by pDNA-VEGF165/CYD-PEI Nanoparticles Loaded Gelatin/β-TCP Matrix as a Therapeutic Agent and Gene Delivery Vehicle for Wound Healing

    June 2013 in “ Molecular Pharmaceutics ”
    Li‐Hua Peng, Wei Wei, Xiaotian Qi … Gao J
    Studysummary This study demonstrates that transfected epidermal stem cells using a novel 3D transfection system significantly enhanced wound healing and may serve as an effective therapeutic agent and gene delivery method for wound treatment.
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    Research cited in this study 4

    1. Transplantation of Bone-Marrow-Derived Mesenchymal and Epidermal Stem Cells Contribute to Wound Healing with Different Regenerative Features Cell and Tissue Research · 2013
    2. Exploring the Role of Stem Cells in Cutaneous Wound Healing Experimental Dermatology · 2009
    3. Stem Cell Markers (Cytokeratin 15, CD34, and Nestin) in Primary Scarring and Nonscarring Alopecia British Journal of Dermatology · 2009
    4. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005