Parallels in Signaling Between Development and Regeneration in Ectodermal Organs
January 2022
in “
Current topics in developmental biology/Current Topics in Developmental Biology
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Research cited in this study
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research A Novel and Safe Small Molecule Enhances Hair Follicle Regeneration by Facilitating Metabolic Reprogramming
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research Suppression of Wnt/β-Catenin Signaling by EGF Receptor Is Required for Hair Follicle Development
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research Embryonic-Like Regenerative Phenomenon: Wound-Induced Hair Follicle Neogenesis
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research Hair Follicle Stem Cell Cultures Reveal Self-Organizing Plasticity of Stem Cells and Their Progeny
This study established a new in vitro culture system that supports the growth and dynamic self-organization of hair follicle stem cells and their progeny, promoting a stable population equilibrium.
research Integrin Signaling Regulates YAP/TAZ to Control Skin Homeostasis
In this study, researchers found that YAP and TAZ, when localized in the nucleus of basal layer cells, are crucial for skin regeneration and hair growth, with their loss leading to slower cell proliferation, hair loss, and impaired wound healing in mice.
research Emerging Interactions Between Skin Stem Cells and Their Niches
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research Signaling Involved in Hair Follicle Morphogenesis and Development
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research Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells
This study found that Shh from neurons signals to Gli1-expressing cells in the hair follicle, cultivating a niche where these bulge cells can potentially transform into epidermal stem cells in wound healing.
research Differential Sensitivity of Epidermal Cell Subpopulations to Beta-Catenin-Induced Ectopic Hair Follicle Formation
In this study, researchers observed that the sebaceous gland niche in mice allows for Wnt-induced hair follicle differentiation, unlike the non-permissive bulge.
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research Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding
Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
research Molecular Mechanisms Regulating Hair Follicle Development
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research Activation of the Notch Pathway in the Hair Cortex Leads to Aberrant Differentiation of the Adjacent Hair-Shaft Layers
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