Paternal Finasteride Exposure and Its Impact on Offspring Testicular Histopathology and Intracellular Junctions: The Role of Occludin and N-Cadherin

    June 2026 in “ Reproductive Biology ”
    Marika Freus, Kamila Misiakiewicz-Has, Anna Pilutin … Agnieszka Kolasa
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    Research cited in this study 24

    1. Long-Term Oral Exposure to Finasteride and Different Doses of Minoxidil Induces Testicular and Epididymal Alterations in Adult Balb/c Mice Toxicology · 2025
    2. The Postnatal Offspring of Finasteride-Treated Male Rats Show Altered ERα and PCNA Expression in the Liver Reproductive Biology · 2025
    3. Comparative Effects of Finasteride and Minoxidil on Male Reproductive Organs: A Systematic Review of In Vitro and In Vivo Evidence Toxicology and Applied Pharmacology · 2023
    4. Paternal Finasteride Treatment Can Influence the Testicular Transcriptome Profile of Male Offspring—Preliminary Study Current Issues in Molecular Biology · 2021
    5. Resveratrol Ameliorates the Seminiferous Tubules Damages Induced by Finasteride in Adult Male Rats Microscopy and Microanalysis · 2020
    6. Post-Finasteride Syndrome: Risks and Side Effects of Finasteride for Androgenetic Alopecia Anais Brasileiros De Dermatologia · 2020
    7. Androgenetic Alopecia: Effects of Oral Finasteride on Hormone Profile, Reproduction, and Sexual Function Endocrine · 2020
    8. Evaluation of Long-Term Efficacy of Finasteride in Korean Men with Androgenetic Alopecia Using the Basic and Specific Classification System Journal of Dermatology · 2018
    9. Infertility and Teratogenicity After Paternal Exposure to Systemic Dermatologic Medications: A Systematic Review Journal of The American Academy of Dermatology · 2018
    10. A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome Urology · 2018
    11. Finasteride Use During Pregnancy and Early Neonatal Outcome: A Case Report International Journal of Clinical Pharmacy · 2018
    12. Connexin 43 Expression in the Testes During Postnatal Development of Finasteride-Treated Male Rat Offspring Archives of Medical Science · 2017
    13. Adverse Effects of Finasteride: Myths and Realities. An Updated Review Revista Medica De Chile · 2016
    14. Guidelines on the Use of Finasteride in Androgenetic Alopecia Indian Journal of Dermatology, Venereology and Leprology · 2016
    15. Androgen Levels and Apoptosis in the Testis During Postnatal Development of Finasteride-Treated Male Rat Offspring Folia Histochemica Et Cytobiologica · 2015
    16. Secondary Infertility Due to Use of Low-Dose Finasteride International Urology and Nephrology · 2012
    17. Finasteride-Induced Secondary Infertility Associated with Sperm DNA Damage Fertility and Sterility · 2011
    18. Finasteride-Associated Male Infertility Fertility and Sterility · 2010
    19. The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men The Journal of Clinical Endocrinology and Metabolism · 2007
    20. Natural Variability and the Influence of Concurrent Control Values on the Detection and Interpretation of Low-Dose or Weak Endocrine Toxicities Environmental Health Perspectives · 2004
    21. Finasteride-Associated Male Infertility Revista do Hospital das Clínicas · 2004
    22. Effects of In Utero Exposure to Finasteride on Androgen-Dependent Reproductive Development in Male Rats Toxicological Sciences · 2003
    23. Effects of Finasteride, a Type 2 5-Alpha Reductase Inhibitor, on Fetal Development in the Rhesus Monkey (Macaca Mulatta) Teratology · 1997
    24. Decreased Fertility in Male Rats Administered the 5α-Reductase Inhibitor, Finasteride, Due to Deficits in Copulatory Plug Formation Reproductive Toxicology · 1991