The Hair Follicle as a Wound Healing Promoter and Its Application in Clinical Practice

    December 2017
    Francisco Jimenez, María Luisa Martínez Martínez, Eduardo Escario, Ander Izeta
    Studysummary This review explores the role of hair follicles in wound healing and suggests future research directions, without presenting new clinical findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 36

    1. Self-Assembling Peptide Hydrogel Scaffolds Support Stem Cell-Based Hair Follicle Regeneration Nanomedicine: Nanotechnology, Biology and Medicine · 2016
    2. Defining the Identity of Mouse Embryonic Dermal Fibroblasts Genesis · 2016
    3. Surface Tension Guided Hanging-Drop: Producing Controllable 3D Spheroids of High-Passaged Human Dermal Papilla Cells and Forming Inductive Microtissues for Hair-Follicle Regeneration ACS Applied Materials & Interfaces · 2016
    4. Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Near the Distal End of the Arrector Pili Muscle Stem Cells International · 2016
    5. Inhibition of β-Catenin Signaling in Dermal Fibroblasts Enhances Hair Follicle Regeneration During Wound Healing Development · 2016
    6. Hair Follicle and Interfollicular Epidermal Stem Cells Make Varying Contributions to Wound Regeneration Cell Cycle · 2015
    7. Fate of Prominin-1 Expressing Dermal Papilla Cells During Homeostasis, Wound Healing, and Wnt Activation Journal of Investigative Dermatology · 2015
    8. Inhibition of Wnt/β-Catenin Pathway Promotes Regenerative Repair of Cutaneous and Cartilage Injury The FASEB Journal · 2015
    9. dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration Cell Stem Cell · 2015
    10. SCF Increases In Utero-Labeled Stem Cells Migration And Improves Wound Healing Wound Repair and Regeneration · 2015
    11. Lack of Collagen VI Promotes Wound-Induced Hair Growth Journal of Investigative Dermatology · 2015
    12. In Vitro Characterization of Human Hair Follicle Dermal Sheath Mesenchymal Stromal Cells and Their Potential in Enhancing Diabetic Wound Healing Cytotherapy · 2015
    13. Wound Healing and Skin Regeneration Cold Spring Harbor Perspectives in Medicine · 2015
    14. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014
    15. Impaired Hair Growth and Wound Healing in Mice Lacking Thyroid Hormone Receptors PloS one · 2014
    16. Dermal Papilla Cells Improve Wound Healing and Generate Hair Bud-Like Structures in Grafted Skin Substitutes Using Hair Follicle Stem Cells Stem Cells Translational Medicine · 2014
    17. Emerging Interactions Between Skin Stem Cells and Their Niches Nature Medicine · 2014
    18. Reflections on How Wound Healing-Promoting Effects of the Hair Follicle Can Be Translated into Clinical Practice Experimental Dermatology · 2014
    19. Elevated Circulation Levels of an Antiangiogenic SERPIN in Patients with Diabetic Microvascular Complications Impair Wound Healing Through Suppression of Wnt Signaling Journal of Investigative Dermatology · 2014
    20. Lineage Analysis of Epidermal Stem Cells Cold Spring Harbor Perspectives in Medicine · 2014
    21. Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth Proceedings of the National Academy of Sciences of the United States of America · 2013
    22. Augmenting Endogenous Wnt Signaling Improves Skin Wound Healing PLoS ONE · 2013
    23. Hypothalamic–Pituitary–Thyroid Axis Hormones Stimulate Mitochondrial Function and Biogenesis in Human Hair Follicles Journal of Investigative Dermatology · 2013
    24. Fgf9 From Dermal γδ T Cells Induces Hair Follicle Neogenesis After Wounding Nature Medicine · 2013
    25. Dermal Papilla Cell Number Specifies Hair Size, Shape, and Cycling, and Its Reduction Causes Follicular Decline Development · 2013
    26. A Pilot Clinical Study of Hair Grafting in Chronic Leg Ulcers Wound Repair and Regeneration · 2012
    27. Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration Journal of Investigative Dermatology · 2012
    28. Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches Nature Communications · 2012
    29. Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences Between Sox2-Positive and Sox2-Negative Cells In Vitro and In Vivo Journal of Investigative Dermatology · 2011
    30. Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells Cell stem cell · 2011
    31. The Basement Membrane Of Hair Follicle Stem Cells Is A Muscle Cell Niche Cell · 2011
    32. De Novo Production of Dermal Papilla Cells During the Anagen Phase of the Hair Cycle Journal of Investigative Dermatology · 2010
    33. SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells Cell stem cell · 2009
    34. Sox2-Positive Dermal Papilla Cells Specify Hair Follicle Type in Mammalian Epidermis Development · 2009
    35. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    36. Reepithelialization of a Full-Thickness Burn from Stem Cells of Hair Follicles Micrografted into a Tissue-Engineered Dermal Template (Integra) Plastic and Reconstructive Surgery · 2004

    Related research 6

    1. Electric Hair Follicular Stimulation Journal of Allergy and Therapy · 2021
    2. Efficacy of Topical Tofacitinib in Promoting Hair Growth in Non-Scarring Alopecia Journal of Investigative Dermatology · 2018
    3. Regulation of Hair Follicle Cycle PubMed · 2014
    4. Dermo-Follicular Proliferation Induced by Paclitaxel and Counteracted by Minoxidil in Mice 2011
    5. Relating Hair Growth Theory and Experimental Evidence to Practical Hair Transplantation The American Journal of Cosmetic Surgery · 1994
    6. Retinoids: Compounds Important to Hair Growth Clinics in dermatology · 1988