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Did you mean Follicular Epithelial Cells?

Glossary Follicular Epithelial Cells

specialized cells lining hair follicles, aiding hair growth

Follicular epithelial cells are specialized cells that line the hair follicles in the skin. They play a crucial role in the growth and development of hair by supporting the hair matrix cells, which are responsible for producing the hair shaft. These cells also help maintain the health and function of the hair follicle, making them essential for normal hair growth and regeneration.

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Research

5 / 1000+ results

research Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment

14 citations , January 2021 in “Stem cell research & therapy”

This study suggests that interfollicular epidermal keratinocytes with stem-like features may serve as an alternative to follicular keratinocytes for hair regeneration by supporting hair follicle morphogenesis in vivo.

research Hair Follicle Stem Cell SLC3A2 Regulates Epithelial Regenerative Properties

September 2025 in “Journal of Investigative Dermatology”

This research found that deleting the SLC3A2 gene in hair follicle stem cells disrupts their maintenance and proper differentiation, leading to hair follicle growth defects and altered skin regeneration through a YAP/Taz-dependent pathway.

Effect of Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate) Nanofiber Matrices Cocultured With Hair Follicular Epithelial and Dermal Cells for Biological Wound Dressing

research Effect of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Nanofiber Matrices Cocultured With Hair Follicular Epithelial and Dermal Cells for Biological Wound Dressing

64 citations , August 2007 in “Artificial Organs”

This study found that PHBV cocultured with epithelial and dermal cells might enhance early-stage wound healing by promoting wound closure and re-epithelization more effectively than PHBV/collagen.

research 917 Frontal fibrosing alopecia scalp profiling links Th1/Th2 and JAK3 activation with fibrosis and loss of follicular stem cells

April 2019 in “Journal of Investigative Dermatology”

Targeting immune pathways like JAK/STAT may help treat frontal fibrosing alopecia.

Epithelial Cells in the Hair Follicle Bulge Do Not Contribute to Epidermal Regeneration After Glucocorticoid-Induced Cutaneous Atrophy

research Epithelial Cells in the Hair Follicle Bulge do not Contribute to Epidermal Regeneration after Glucocorticoid-Induced Cutaneous Atrophy

23 citations , July 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that follicular stem cells in hair follicles are more sensitive to the antiproliferative effects of glucocorticoids compared to basal keratinocytes due to incomplete desensitization.

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Learn

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learn Stem Cell Factor

How does stem cell factor help activate dormant hair follicles? Stem cell factor activates dormant hair follicles by signaling through the c-Kit receptor.

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Overview

learn Apple stem cell

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Community Join

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community Quote from Pelage (PP-405) Spokesperson...

122 upvotes 11 months ago

Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

community Prevention of age-related beard graying in humans by the topical application of Eriodictyon angustifolium extract

5 upvotes 4 years ago

Topical application of Eriodictyon angustifolium extract can prevent and reverse age-related beard graying and darken gray hair by increasing melanin production. Sterubin, a component of the extract, also promotes hair pigmentation and protects cells from DNA damage.

community Got my Oleic fatty acid they used in Korean study. Fuck you mice!

247 upvotes 8 months ago

Oleic acid and microneedling are being explored for hair regrowth, but results are mixed. Addressing DHT and fibrosis is crucial, with treatments like finasteride, minoxidil, and scalp massage also discussed.

community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

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