Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society Clinical Practice Guideline

Oral contraceptives and antiandrogens are effective for treating hirsutism, with antiandrogens being the most effective.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.

Some medicines can reduce excessive hair growth in women, but more research is needed to compare treatments and consider side effects.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

A simplified scoring system can effectively diagnose hirsutism in Chinese women of reproductive age.

Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

An mFG score of 5 or more indicates above-normal hair growth in Southern Chinese women.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Both intense pulsed light and long-pulsed diode laser effectively reduced facial hair in women, with no significant difference in satisfaction after 6 months, but intense pulsed light was more painful.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Combining eflornithine cream with laser treatment removes facial hair better than laser alone.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

The cream effectively and safely reduces facial hair in women.

Eflornithine cream slows facial hair growth and works well with other treatments.

Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.

The document likely offers guidance on treating a woman's excessive hair growth, considering her symptoms and obesity.

Finasteride cream didn't significantly reduce hair more than a placebo, but users felt it helped.

Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.

Very few people experience increased hair growth after laser hair removal, especially those with darker skin and black hair.

Finasteride reduces hirsutism effectively with fewer side effects but is a second-choice treatment due to safety concerns.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

Cyproterone acetate with estradiol may subjectively improve excessive hair growth in women, but it's not clinically better than other treatments.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.

Vaniqa cream slows unwanted facial hair growth in women.

The guidelines help doctors diagnose and treat hormone-related disorders in women.

Finasteride cream reduces hair growth in women with hirsutism, but more research needed.

Flutamide reduces hair growth better but has more side effects.

Both finasteride and GnRH agonist treatments reduced hair growth in women with idiopathic hirsutism, but GnRH agonist was more effective.

Spironolactone most effective for hirsutism, but has side effects.

The normal-mode ruby laser effectively reduces facial hair for a long time with few side effects.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

Laser hair removal is safe with the right settings, but side effects like pain and skin changes are more common in darker or tanned skin.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.

Finasteride reduces hair growth better, but spironolactone has more side effects.

Hormone therapy for excessive hair growth is as good with GnRHa as with high-dose CPA, but GnRHa has longer-lasting results.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

The oral contraceptive alone is the preferred treatment for hirsutism, as adding the GnRH analog showed no significant benefit.

Leuprolide plus estrogen is more effective than oral contraceptives for reducing hirsutism.

Combining a GnRH agonist with a low-dose oral contraceptive is more effective and safer for treating hirsutism than using either alone.

Electrolysis is effective for permanent hair removal, but technique is key to avoid scarring, and sometimes hormonal treatment is needed for women with hirsutism.

Medication and hair removal methods can improve hirsutism, but no drugs were specifically approved for it in North America as of 1995.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Flutamide, a medication used for excessive hair growth, can cause severe liver damage in women.

The ovary mainly causes high testosterone in PCO, while the adrenal gland is the main source in IH.

Lower doses of dexamethasone can safely reduce high DHEAS levels in women with androgenic disorders.

Chronic GnRHa treatment can help manage endometrial hyperplasia and reduce ovarian androgen excess in PCO patients.

The spironolactone cream did not reduce hair growth in women with hirsutism.

Nafarelin may effectively treat excessive hair growth in women by reducing certain hormone levels.

Spironolactone reduced hair thickness and some testosterone levels in women with excessive hair growth.

Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.