American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the Diagnosis and Treatment of Hyperandrogenic Disorders

March 2001 in “ Endocrine practice ”

Neil F. Goodman, Maya B. Bledsoe, Rhoda H. Cobin, Walter Futterweit, Joseph W. Goldzieher, Steven M. Petak, Keith D. Smith, Emil Steinberger

hirsutism acne alopecia amenorrhea infertility hyperandrogenic disorders hypertension microvascular disease dyslipidemias type 2 diabetes mellitus hair loss high blood pressure high cholesterol diabetes

TLDR The guidelines help doctors diagnose and treat hormone-related disorders in women.

The document provided guidelines for diagnosing and treating hyperandrogenic disorders in women, which include symptoms like hirsutism, acne, alopecia, amenorrhea, and infertility. It highlighted the role of clinical endocrinologists in managing these conditions due to their potential link to serious cardiovascular and metabolic issues, such as hypertension, microvascular disease, dyslipidemias, and type 2 diabetes mellitus. The guidelines aimed to offer a practical summary of accepted scientific information and recommendations for clinical practice, rather than an exhaustive literature review or analysis of recent advances.

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8 / 8 results

research Androgens and Women's Health

5 citations , June 1998 in “PubMed”

Excessive androgen in women can cause acne, hair growth, baldness, and PCOS, often treatable with medication.

research Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up

75 citations , November 1996 in “Fertility and Sterility”

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

research Clinical and Endocrine Effects of Finasteride, a 5α-Reductase Inhibitor, in Women with Idiopathic Hirsutism

70 citations , August 1995 in “Fertility and Sterility”

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

research Comparison of Sequential Cyproterone Acetate/Estrogen Versus Spironolactone/Oral Contraceptive in the Treatment of Hirsutism

68 citations , May 1991 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

Both cyproterone acetate and spironolactone effectively reduce hair growth in women with hirsutism.

research The Treatment of Hyperandrogenism with Oral Contraceptives

25 citations , August 1989 in “Seminars in reproductive medicine”

Birth control pills are effective for treating women with too much male hormone.

research Spironolactone in combination drug therapy for unresponsive hirsutism

44 citations , June 1985 in “Fertility and sterility”

Combination drug therapy is effective for hirsutism that doesn't improve with just one medication.

research 3 alpha, 17 beta-androstanediol glucuronide in plasma. A marker of androgen action in idiopathic hirsutism.

179 citations , May 1982 in “The Journal of clinical investigation/The journal of clinical investigation”

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.

research Treatment of Hirsutism With Spironolactone

183 citations , March 1982 in “JAMA”

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

4 / 4 results

research Severe Hyperandrogenemia and Insulin Resistance in a 12-Year-Old Girl

2 citations , August 2012 in “Journal of Pediatric and Adolescent Gynecology”

A 12-year-old girl with very high testosterone and insulin resistance improved with birth control pills, suggesting PCOS can cause high testosterone without tumors.

research Hyperandrogenism in Women: Polycystic Ovary Syndrome

3 citations , January 2012 in “Hanyang Medical Reviews”

The document concludes that more research is needed to create suitable diagnostic criteria and understand PCOS in Korean women, and genetics may allow for personalized treatment.

research Diagnosis of Hyperandrogenism: Clinical Criteria

85 citations , June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism”

The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.

research Hirsutism and Virilization

13 citations , January 1995 in “Postgraduate medicine”

Excessive hair growth in women can be harmless or signal serious health issues, and treatment often includes medication and hair removal, with noticeable results after 3-6 months.