Hirsutism and Virilization

    January 1995 in “ Postgraduate medicine ”
    Paul B. Marshburn, Bruce R. Carr
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    TLDR Excessive hair growth in women can be harmless or signal serious health issues, and treatment often includes medication and hair removal, with noticeable results after 3-6 months.
    The 1995 article addresses hirsutism, excessive hair growth in women, noting that it is often benign but can indicate serious conditions like tumors. It is frequently associated with menstrual disorders and an increased risk of endometrial cancer, commonly resulting from polycystic ovarian syndrome or increased androgen. Diagnosis focuses on excluding dangerous causes, with serum testosterone and dehydroepiandrosterone sulfate levels aiding in identifying ovarian or adrenal origins. Treatment typically involves a combination of weight loss, oral contraceptives, antiandrogens like spironolactone, and mechanical hair removal methods, with surgery as an option for severe cases. Improvement is usually seen after 3 to 6 months of treatment. The authors emphasize the importance of ruling out life-threatening causes promptly, as rapid progression of hair growth can signal endocrinopathies or tumors.
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