Comparative Efficacy of Non-Transplant Interventions for Female Pattern Hair Loss: A Systematic Review and Network Meta-Analysis

    July 2026 in “ Journal of Cosmetic Dermatology ”
    Caixia Hu, X Z Li, Wenqing Wang … Yi Cheng
    Studysummary This network meta-analysis found that for female pattern hair loss, microneedling combined with minoxidil ranked highest for hair density and patient satisfaction, while poly-L-lactic acid threads plus minoxidil led in hair diameter; however, the evidence is uncertain and lacks placebo-controlled trials.
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    Research cited in this study 24

    1. Female Pattern Hair Loss: Therapeutic Update Anais Brasileiros De Dermatologia · 2023
    2. Hair Regrowth Treatment Efficacy and Resistance in Androgenetic Alopecia: A Systematic Review and Continuous Bayesian Network Meta-Analysis Frontiers in Medicine · 2023
    3. Use of Autologous Platelet-Rich Plasma in Androgenetic Alopecia in Women: A Systematic Review and Meta-Analysis Journal of Dermatological Treatment · 2022
    4. Randomized Trial of Microneedling Combined With 2% Minoxidil Topical Solution for the Treatment of Female Pattern Hair Loss in a Chinese Population Journal of Cosmetic Dermatology · 2022
    5. Efficacy and Safety of 5% Minoxidil Alone, Minoxidil Plus Oral Spironolactone, and Minoxidil Plus Microneedling on Female Pattern Hair Loss: A Prospective, Single-Center, Parallel-Group, Evaluator-Blinded, Randomized Trial Frontiers in Medicine · 2022
    6. Randomized Clinical Trial of Low-Dose Oral Minoxidil for the Treatment of Female Pattern Hair Loss: 0.25 mg Versus 1 mg Journal of The American Academy of Dermatology · 2022
    7. A Randomized Clinical Trial on Therapeutic Effects of 0.25 mg Oral Minoxidil Tablets on Treatment of Female Pattern Hair Loss Dermatologic Therapy · 2021
    8. Female Pattern Hair Loss: A Comprehensive Review Dermatologic Therapy · 2020
    9. Topical Finasteride for the Treatment of Male Androgenetic Alopecia and Female Pattern Hair Loss: A Review of the Current Literature Journal of Dermatological Treatment · 2020
    10. The Effectiveness of Combination Therapies for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Dermatologic Therapy · 2020
    11. Evaluation of the Efficacy and Safety of Cow Placenta Extract Lotion Versus Minoxidil 2% in the Treatment of Female Pattern Androgenetic Alopecia International Journal of Women's Dermatology · 2020
    12. Efficacy of Non-Surgical Treatments for Androgenetic Alopecia in Men and Women: A Systematic Review with Network Meta-Analyses and an Assessment of Evidence Quality Journal of Dermatological Treatment · 2020
    13. Accelerated Hair Growth by Combining Thread Monofilament and Minoxidil in Female Androgenetic Alopecia Journal of Cosmetic Dermatology · 2019
    14. Monofilament Threads in Treatment of Female Hair Loss Journal of Dermatological Treatment · 2019
    15. Minoxidil 1 mg Oral Versus Minoxidil 5% Topical Solution for the Treatment of Female-Pattern Hair Loss: A Randomized Clinical Trial Journal of The American Academy of Dermatology · 2019
    16. Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis Journal of The European Academy of Dermatology and Venereology · 2018
    17. Scalp Threading with Polydioxanone Monofilament Threads: A Novel, Effective, and Safe Modality for Hair Restoration Journal of The European Academy of Dermatology and Venereology · 2017
    18. Low-Level Light and Minoxidil 5% Combination Versus Either Modality Alone in Management of Female Patterned Hair Loss: A Randomized Controlled Study Lasers in Surgery and Medicine · 2017
    19. Genetics and Other Factors in the Etiology of Female Pattern Hair Loss Experimental Dermatology · 2017
    20. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    21. The Use of Low-Level Light Therapy in the Treatment of Androgenetic Alopecia and Female Pattern Hair Loss Journal of Dermatological Treatment · 2013
    22. A Randomized, Single-Blind Trial of 5% Minoxidil Foam Once Daily Versus 2% Minoxidil Solution Twice Daily in the Treatment of Androgenetic Alopecia in Women Journal of The American Academy of Dermatology · 2011
    23. Medical Treatments for Male and Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2008
    24. Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2001