A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia?

    May 2021 in “ Biomedicines ”
    Ivan Jozic, Jérémy Chéret, Beatriz Abdo Abujamra … Ralf Paus
    Studysummary This review explores the potential role of caveolin-1 in cicatricial alopecia, particularly frontal fibrosing alopecia, and discusses possibilities for targeted therapies without providing new research results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 35

    1. Hormonal Contraceptives And Dermatology American Journal of Clinical Dermatology · 2020
    2. Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata Experimental dermatology · 2020
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    8. Genome-Wide Association Study in Frontal Fibrosing Alopecia Identifies Four Susceptibility Loci Including HLA-B*07:02 Nature Communications · 2019
    9. Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study Skin appendage disorders · 2019
    10. Olfactory Receptor OR2AT4 Regulates Human Hair Growth Nature Communications · 2018
    11. Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases Trends in Molecular Medicine · 2018
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    22. Lichen Planopilaris Is Characterized By Immune Privilege Collapse Of The Hair Follicle's Epithelial Stem Cell Niche The Journal of Pathology · 2013
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    27. Expression of Snail1 in the Fibrotic Dermis of Postmenopausal Frontal Fibrosing Alopecia: Possible Involvement of an Epithelial-Mesenchymal Transition and a Review of Japanese Patients British Journal of Dermatology · 2010
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    Related research 4

    1. Understanding Immune Privilege in an Inducible Mouse Model of Primary Cicatricial Alopecia ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2023
    2. Feature Characterization of Scarring and Non-Scarring Types of Alopecia by Multiphoton Microscopy Lasers in Surgery and Medicine · 2018
    3. The Immunopathobiology of Lichen Planopilaris [Thesis]. Manchester, UK: The University of Manchester; 2011. · 2011
    4. Does Collapse of Immune Privilege in the Hair-Follicle Bulge Play a Role in the Pathogenesis of Primary Cicatricial Alopecia? Clinical and Experimental Dermatology · 2009