Androgenetic Alopecia

    Gökhan ŞAHİN, Hilal Ozdemir, Fatma Aydın
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    TLDR The review provided information on various treatments to stop hair thinning and increase hair density in people with common genetic hair loss.
    Three years ago, a review was conducted on the management of androgenetic alopecia, a common form of hair loss in genetically predisposed individuals. The review noted that there was no standard treatment guideline for this condition, with the goal of management being to halt follicular miniaturization and increase hair density. Various therapies were used, including potassium ion channel modifiers (like topical and oral minoxidil), 5α reductase inhibitors (like oral finasteride, topical finasteride, and oral dutasteride), androgen receptor antagonists, other medical treatments, physical treatments, complementary therapies, and combination therapies. The review aimed to provide information about these current treatment methods for both men and women.
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      in Research/Science  737 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.
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      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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