19 citations,
January 2018 in “BioMed Research International” miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.
55 citations,
October 2014 in “Development” Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.
30 citations,
February 2017 in “Histochemistry and Cell Biology” TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.
25 citations,
September 2018 in “Molecular Biology of the Cell” Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
25 citations,
April 2015 in “Journal of Investigative Dermatology” GasderminA3 is important for normal hair cycle transitions by controlling Wnt signaling.
24 citations,
March 2020 in “Cells” Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.
29 citations,
December 2012 in “Fibrogenesis & Tissue Repair” Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
24 citations,
March 2018 in “Pigment Cell & Melanoma Research” The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.
May 2023 in “Research Square (Research Square)” Shi-Bi-Man activates hair follicle stem cells and promotes hair growth by changing lactic acid metabolism and other cellular processes.
1 citations,
July 2023 in “Chinese Medicine” Shi-Bi-Man, a Traditional Chinese Medicine, helps grow hair by boosting lactic acid metabolism and activating hair follicle stem cells.
57 citations,
March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
12 citations,
May 2023 in “EMBO reports” High mTORC1 activity slows hair growth and causes it to lose color.
5 citations,
May 2022 in “Biomedicines” Botryococcus terribilis and its compounds may promote hair growth and improve hair health.
July 2019 in “Journal of Investigative Dermatology” The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.
68 citations,
May 2018 in “PLOS Biology” Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.
10 citations,
May 2020 in “Journal of Dermatological Treatment” Microneedling with 5% minoxidil improves hair loss in Chinese men by activating Wnt/ß-catenin pathway.
5 citations,
November 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.
1 citations,
July 2022 in “British Journal of Dermatology” Targeting specific genes in certain pathways may help treat male pattern baldness.
18 citations,
January 2019 in “Experimental Dermatology” Certain cells outside the hair follicle's bulge area can quickly regenerate damaged hair follicles, potentially helping to reduce hair loss from cancer treatments.
Targeting CXXC5 and GSK-3β may help treat male pattern baldness.
29 citations,
January 2021 in “Journal of Investigative Dermatology” Fat under the skin releases HGF which helps hair grow and gain color.
160 citations,
January 2014 in “Seminars in cell & developmental biology” Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
3 citations,
June 2020 in “Developmental Cell” Feather patterns are influenced by enhancers and chromatin looping, and the structure of protein complexes important for hair growth has been detailed.
30 citations,
December 2018 in “Trends in Endocrinology and Metabolism” Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.
Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.
May 2021 in “Experimental Cell Research” FOXC1 boosts SFRP1 in hair loss, suggesting new treatments.
53 citations,
February 2020 in “Expert Opinion on Pharmacotherapy” Finasteride and minoxidil work best together for hair loss.
39 citations,
April 2020 in “IntechOpen eBooks” Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
7 citations,
July 2020 in “Pigment cell & melanoma research” RT1640 treatment reverses gray hair and promotes hair growth in mice.
6 citations,
October 2020 in “Journal of Cellular and Molecular Medicine” 3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.