10 citations
,
June 2018 in “Journal of visualized experiments” This study demonstrated that lactate dehydrogenase activity is notably high in quiescent hair follicle stem cells within mouse skin using a specific enzymatic activity assay.
7 citations
,
October 2018 in “Dermatology practical & conceptual” This study found that topical oxygen therapy may be a beneficial adjuvant treatment for hair loss, acne, and chronic dermatological conditions, though further research is needed to confirm its effectiveness.
January 2024 in “Wiadomości Lekarskie” This preclinical study found that exercise-induced extracellular vesicles delayed breast cancer tumor growth in mice, potentially by enhancing the immune response within the tumor microenvironment.
9 citations
,
August 2019 in “Journal of The European Academy of Dermatology and Venereology” Minoxidil activation by hair enzymes predicts treatment success for female hair loss.
48 citations
,
May 2002 in “Journal of Anatomy” The researchers reported that VEGF increases vascular permeability in mesenteric microvessels of anaesthetized frogs through specific cellular pathways involving tyrosine autophosphorylation and PLC activation.
5 citations
,
February 2025 in “International Journal of Molecular Sciences” This study investigated pyranoanthocyanin Vitisin A and found it significantly lowered triglyceride levels and reduced body weight in high-fat diet-fed mice, outperforming Cyanidin-3-O-glucoside by inhibiting hepatic lipogenesis and enhancing fatty acid β-oxidation.
20 citations
,
February 1977 in “Circulation” Minoxidil lowers blood pressure and increases heart efficiency, but may raise lung artery pressure in some people.
11 citations
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November 2018 in “British Journal of Dermatology” In this study, adults with persistent facial erythema of rosacea showed significantly greater improvement when treated with once-daily oxymetazoline cream compared to a vehicle, and using baseline photographs in assessments enhanced the accuracy by reducing perceived vehicle effects.
20 citations
,
October 2004 in “Journal of Pharmaceutical and Biomedical Analysis” Quick method to measure minoxidil in blood, accurate and useful for labs.
This study reported that pentoxifylline-loaded liposomes, optimized using a statistical design method, achieved a maximum encapsulation efficiency of 84.23% and a controlled 72-hour drug release, potentially improving therapeutic delivery of the drug with limited bioavailability.
February 2023 in “Frontiers in Bioengineering and Biotechnology” This review discusses the potential of optical techniques for diagnosing and treating oxidative stress-related hepatic ischemia-reperfusion injury, highlighting the need for non-invasive diagnostic methods and the anti-oxidative potential of optical therapies; it reports no new clinical results.
35 citations
,
October 2017 in “Trends in Molecular Medicine” This research suggests that targeting the HIF-1α pathway via PHD inhibitors may enable regeneration similar to amphibians in mammals, potentially fast-tracking regenerative therapies from mice to humans.
April 2022 in “UNESP Institutional Repository (São Paulo State University)” This study found that the combination of topical minoxidil and oral biotin significantly increased hair growth speed and density in healthy men, while neither intervention alone had a significant effect.
August 2025 in “Indian Dermatology Online Journal” This study found that combining topical minoxidil with phototherapy significantly improved pigmentation and reduced vitiligo severity compared to placebo, as measured by VASI scores over 12 weeks, though the sample size was small and follow-up short.
11 citations
,
March 2007 in “Journal of Hypertension” This article provides contact information for Professor A. Brew Atkinson and reports no new research findings; it is not a study abstract.
18 citations
,
March 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, 17β-estradiol increased VEGF production in differentiated THP-1 cells, while dihydrotestosterone counteracted this effect by modulating adenylate cyclase activity.
April 2026 in “The Open Biotechnology Journal” This review reports that resveratrol could benefit the management of chronic illnesses such as diabetes and cardiovascular disease, but challenges with bioavailability and regulatory issues persist.
3 citations
,
June 2022 in “e-Journal of Cardiovascular Medicine” This study found no significant difference in the ability of ischemia modified albumin and exercise electrocardiograms to determine myocardial ischemia in patients with stable angina pectoris.
6 citations
,
October 2018 in “Lasers in Medical Science” This article explores the potential of photobiomodulation for coronary health, suggesting protective effects after heart attacks and in inaccessible ischemic heart conditions, but presents no new clinical results.
6 citations
,
January 1988 in “PubMed” In this study, no changes in cutaneous blood flow were observed after applying 2%, 5%, or placebo minoxidil lotion in both androgenetic alopecia and healthy male volunteers.
3 citations
,
August 2023 in “Biophysical Journal” In this study, researchers found that epithelial cells exhibit density-dependent metabolic heterogeneity, particularly in the pre-epithelial transition stage, where metabolic patterns correlate with cell proliferation and are influenced by actomyosin contractility.
This study found that sulfotransferase enzyme levels significantly impact the effectiveness of minoxidil in treating androgenetic alopecia, suggesting that testing for this enzyme could help identify potential responders before treatment.
61 citations
,
March 1981 in “Circulation” Minoxidil improves blood flow in heart failure patients.
May 2025 in “UNESP Institutional Repository (São Paulo State University)” In this randomized clinical trial, minoxidil at 5 mg was not found to be superior to 2.5 mg for treating male androgenetic alopecia over 24 weeks, though the higher dose more frequently caused side effects like pre-tibial edema and dizziness.
April 2025 in “Experimental Eye Research” In this study, researchers characterized the retinal structure and function of the Oatrhg mouse model of gyrate atrophy, finding localized atrophy without significant retina-wide functional impact, suggesting the model may be useful for testing new treatments using multimodal retinal imaging.
2 citations
,
February 2022 in “Biology” This study found that blue laser irradiation reduced ATP levels and cell viability in mouse skin by increasing oxidative stress through the production of reactive oxygen species.
January 2026 in “Burns & Trauma” Low oxygen and metabolic changes help organoids grow and repair tissues.
December 2014 in “Journal of Biomedical Research” In a mouse model of peripheral vascular disease, this study found that recombinant thymosin β4 treatment increased expression levels of certain proteins, promoting angiogenesis.
January 2005 in “Linchuang pifuke zazhi” In this study, transfection of the VEGF165 gene increased hair growth and rejuvenated the atrophic dermis in a mouse model of sclerotic skin.
October 2018 in “Exercise Biochemistry Review” In this mouse study, aerobic exercise was found to protect the intestinal mucosal barrier in obstructive jaundice by inhibiting the HMGB1 / TLR4 / NF-κB signaling pathway through the H2S / CSE system.