Intraretinal Variation in Disease Severity in the Oat Mouse Model of Gyrate Atrophy

    April 2025 in “ Experimental Eye Research ”
    Russell M. Wilder, Andrea An, Brent A. Bell … Katherine E. Uyhazi
    Studysummary In this study, researchers characterized the retinal structure and function of the Oat<sup>rhg</sup> mouse model of gyrate atrophy, finding localized atrophy without significant retina-wide functional impact, suggesting the model may be useful for testing new treatments using multimodal retinal imaging.
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    Research cited in this study 1

    1. The Retarded Hair Growth Mutation in Mice Is an Allele of Ornithine Aminotransferase Molecular Genetics and Metabolism Reports · 2014