Efficacy of Topical 5% Minoxidil Versus Oral 5mg Biotin Versus Topical Minoxidil and Oral Biotin on Hair Growth Velocity in Men: A Randomized, Crossover Clinical Trial

The study investigated the effects of topical 5% minoxidil, oral 5mg biotin, and their combination on hair growth velocity in 10 healthy men. The randomized, crossover clinical trial found that the combination of topical minoxidil and oral biotin significantly increased hair growth velocity (p=0.02) and hair density (p<0.01) compared to either treatment alone, which did not show significant effects. The average hair growth velocity without intervention was 2.35 mm per week. The findings suggested that the combination treatment was effective in enhancing hair growth and density in the study participants.