Efficacy of 2.5mg Oral Biotin Versus 5% Topical Minoxidil in Increasing Nail Growth Rate

This study compared the efficacy of 2.5 mg oral biotin and 5% topical minoxidil in increasing nail growth rate among 37 healthy adult volunteers. Participants were divided into four groups: control, exclusive minoxidil, exclusive biotin, and combined treatment. Results showed that minoxidil increased nail growth rate by 17%, biotin by 13%, and the combination by 15%. Minoxidil was more effective than biotin alone, but the combination did not outperform minoxidil alone. Both treatments significantly increased nail growth compared to the control, with minoxidil showing superior results over biotin.