TLDR Using both minoxidil and biotin together increased hair growth more than using either one alone.
A randomized, crossover, clinical trial was conducted on 10 healthy male participants to evaluate the effectiveness of oral biotin (5 mg daily), topical minoxidil (5% twice daily), and a combination of both in increasing hair growth rate (HGR). The interventions were applied for a period of 14 days each. The results showed a significant increase in HGR and the photographic area covered by hair only in the group that used the combination of topical minoxidil and oral biotin. The isolated use of both substances did not present a positive result in increasing growth velocity. The study suggests a potential synergistic effect of biotin and minoxidil on hair growth, but more studies are needed to analyze the benefit of long-term use of the combination.
4 citations,
March 2021 in “Experimental dermatology” Minoxidil increases nail growth more than biotin.
53 citations,
August 2019 in “Journal of The American Academy of Dermatology” Oral minoxidil and topical minoxidil 5% both effectively improve female-pattern hair loss with safe side effects.
117 citations,
August 2019 in “Drug Design Development and Therapy” Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.
134 citations,
December 2018 in “Dermatology and Therapy” Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.
178 citations,
April 2017 in “Journal of The American Academy of Dermatology” Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.
August 2023 in “Journal of Cosmetic Dermatology” Some plants like spinach, broccoli, and matcha may boost the effectiveness of the hair growth drug minoxidil.
8 citations,
April 2019 in “Dermatologic Therapy” Tretinoin boosts minoxidil's effect on hair loss by increasing enzyme activity.
5 citations,
January 2018 in “Italian journal of dermatology and venereology” Minoxidil effectively stimulates hair growth in androgenetic alopecia.
14 citations,
January 2015 in “Skin appendage disorders” Minoxidil treatment for hair loss can cause scalp allergy and severe hair loss.
1 citations,
January 2010 Mesotherapy is more effective than topical spray for female hair loss treatment.
269 citations,
August 2002 in “Journal of The American Academy of Dermatology” 5% minoxidil works better for hair growth and density, with minor irritation.
39 citations,
March 1987 in “Journal of The American Academy of Dermatology” Topical minoxidil is a safe and effective treatment for hair loss caused by androgenetic alopecia.
20 citations,
February 1985 in “Archives of Dermatology” Minoxidil helps hair regrowth, especially with more indeterminate hairs.
