Potential Applications of Topical Oxygen Therapy in Dermatology

    October 2018 in “ Dermatology practical & conceptual ”
    Luigi Bennardo, Ester Del Duca, Stefano Dastoli, Giusy Schipani, Elisabetta Scali, Martina Silvestri, Steven Paul Nisticò
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    TLDR Topical oxygen therapy may improve treatments for hair loss, acne, and chronic skin diseases with minimal side effects.
    The document from 2018 reviews the effectiveness of topical oxygen therapy in dermatology, particularly for hair loss, acne, and chronic skin conditions. A study with 30 patients showed that combining 5% minoxidil with oxygen therapy significantly improved hair loss treatment outcomes. In acne treatment, one study demonstrated a substantial reduction in acne lesions after combining oxygen therapy with a phytotherapeutic drug, while another with 18 patients found that adding oxygen therapy to clindamycin lotion greatly reduced the number of facial lesions. For chronic skin diseases like psoriasis and atopic dermatitis, studies with 24 patients each reported significant improvements in disease severity indices and sustained results with minimal side effects. The document concludes that topical oxygen therapy can be an effective adjunctive treatment for these dermatological conditions, but emphasizes the need for larger, more rigorous studies to confirm these findings.
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