Rapid Determination of Minoxidil in Human Plasma Using Ion-Pair HPLC

October 2004 in “ Journal of Pharmaceutical and Biomedical Analysis ”

Afshin Zarghi, Alireza Shafaati, Seyed Mohsen Foroutan, Arash Khoddam

minoxidil ion-pair HPLC human plasma Rogaine

Studysummary Quick method to measure minoxidil in blood, accurate and useful for labs. Our plain-language summary of this paper — not a Tressless recommendation.

This study developed a rapid and sensitive method for analyzing minoxidil in human plasma using ion-pair HPLC. The method has a minimum detectable limit of 0.5 ng ml-¹ and is suitable for routine application in clinical laboratories. The plasma concentrations of minoxidil were determined in 12 healthy volunteers who received 20 mg of minoxidil each, and the results were in agreement with previous reports.

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Research cited in this study

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research The Pharmacokinetics of 2.5- to 10-mg Oral Doses of Minoxidil in Healthy Volunteers

25 citations , February 1989 in “The Journal of Clinical Pharmacology”

This document studied minoxidil in healthy volunteers. Minoxidil is quickly absorbed and eliminated from the body.

research Minoxidil

5 citations , January 1988 in “Analytical profiles of drug substances”

Minoxidil helps lower blood pressure and can also promote hair growth.

research Radioimmunoassay of Minoxidil in Human Serum

21 citations , September 1977 in “Journal of Pharmaceutical Sciences”

This study developed a specific radioimmunoassay to measure minoxidil levels in human serum directly from a single oral dose.