4 citations
,
January 2016 in “Methods in molecular biology” This chapter reviews the methodology for isolating and differentiating CD34+ HAP stem cells into neural cells, but provides no new research results.
21 citations
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March 2025 in “Journal of Extracellular Vesicles” This review discusses how using hydrogels as a three-dimensional culture platform for mesenchymal stem cells might affect the production of extracellular vesicles, highlighting challenges in standardization and opportunities to boost EV yield via combined hydrogels and bioreactor methods.
52 citations
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October 2005 in “Journal of Investigative Dermatology” This study found that human hair follicle stem cells formed more colonies and adhered more rapidly, while transit-amplifying cells showed significantly greater mobility.
July 2026 in “Pharmaceuticals” This review highlights significant research trends and challenges in utilizing plant-derived extracellular vesicles for drug delivery and biomedical applications, emphasizing the need for standardized protocols and advanced purification technologies.
1 citations
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September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that skin-resident and recruited γδ T cells play a crucial role in an early wound healing response following cutaneous vaccinia virus infection, rather than in controlling virus replication.
September 2019 in “Journal of Investigative Dermatology” This study found that co-culturing dermal papilla cells in a 3D structure with adipose-derived stem cells may enhance the expression of hair inductivity markers compared to 2D cultures.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers observed that blood vessel maturation in mice involves neonatal endothelial cells expanding the capillary network through vessel regression and angiogenesis, with adult cells later maintaining stability and repair through specific signaling pathways.
October 2025 in “International Journal of Molecular Sciences” This study demonstrated that a novel hydrogel combining extracellular vesicles from chemically induced mammary epithelial cells with chitosan significantly enhanced skin wound healing in a rat model.
4 citations
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January 2016 in “Methods in molecular biology” This study found that hair-follicle-associated pluripotent stem cells can promote nerve repair and growth in a 3D culture model and potentially differentiate into cardiac muscle cells, offering advantages over other stem cell types for regenerative medicine.
September 2024 in “Advanced Biomedical Research” In this study, chick embryo extract enhanced neuronal differentiation and trophic factor expression in rat hair follicle stem cells, suggesting potential improvements for stem cell therapies in neurodegenerative diseases.
January 2021 in “Mastology” This study found that over 80% of women treated with paclitaxel who used a hypothermic glycerin-based hydrogel cap preserved at least 50% of their initial hair volume, suggesting scalp cooling may effectively prevent chemotherapy-induced alopecia.
January 2008 in “Yearbook of Dermatology and Dermatologic Surgery” Scientists can make stem cells that can turn into any cell type.
April 2017 in “Plastic and reconstructive surgery. Global open” In this study with a rat muscle defect model, decellularized muscle matrix demonstrated better integration, neovascularization, and myogenesis compared to commercially available acellular dermal matrices, and also showed trends toward reduced inflammation and fibrosis after 30 and 60 days.
36 citations
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February 2017 in “Journal of Cellular and Molecular Medicine” In this study, VEGF165 induced hair follicle stem cells to differentiate into vascular endothelial cells, potentially supporting angiogenesis and neovascularization, with the Notch signaling pathway affecting differentiation efficiency.
6 citations
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July 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” This study observed that HAP stem cells from the whiskers of young mice near the ear differentiated into heart-muscle cells more efficiently than those from older mice or other whisker locations.
14 citations
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July 2022 in “Applied Sciences” This review discusses the potential of extracellular vesicles as cell-free tools in tissue engineering and regenerative medicine, noting their emerging role in promoting tissue repair without the risk of host rejection.
CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.
91 citations
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March 2011 in “Stem Cell Reviews and Reports” This article describes protocols for isolating and expanding human epidermal neural crest stem cells and discusses their potential for cell-based therapies in regenerative medicine, but reports no new clinical results.
January 2019 in “Springer eBooks” The abstract reports that non-cultured cellular grafting has become a prevalent and cost-effective method for treating stable vitiligo, with safety and effectiveness confirmed by two decades of studies. It critiques strict legislative oversight, suggesting it might unnecessarily increase costs and limit patient access.
47 citations
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March 2019 in “Journal of immunology research” This review discusses the effects of valproic acid on immune cell activation and gene expression, potentially influencing infection outcomes and suggesting its promise for autoimmune and hypersensitivity condition management.
October 2014 in “Microscopy” This study found that using ionic liquid for specimen preparation allowed for observation of dermal papilla cells and their cilia in near-living conditions, reducing damage typically caused by conventional preparation methods.
December 2019 in “Reproduction Fertility and Development” This study found that mouse embryonic fibroblasts better supported the growth and maintenance of LGR5+ epidermal stem cells compared to porcine fetal fibroblasts, under various culture conditions.
18 citations
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July 2012 in “Cell Biology International Reports” This study suggests that human mesenchymal stem cells have the potential to differentiate into dermal papilla cells both in vitro and in vivo.
14 citations
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May 2019 in “Experimental Dermatology” In this study, adipose tissue secretome was shown to enhance oxidative stress resistance and promote cell proliferation in vitiligo cells, suggesting a potential natural treatment approach.
December 2024 in “Stem Cell Research & Therapy” This study found that OCT4-overexpressing human hair follicle mesenchymal stem cells show promise for artificial hematopoiesis by enhancing self-renewal through cytoskeletal remodeling and the beta-catenin-dependent adherens junction pathway.
7 citations
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November 2022 in “Biochemical and Biophysical Research Communications” This study investigated the heterogeneity of CD34+ cells in wound healing, identifying distinct cell clusters and suggesting potential therapeutic approaches for anagen and diabetic wounds.
April 2026 in “Frontiers in Bioengineering and Biotechnology” This study found that a cellulose membrane significantly shortened the healing time and reduced the ulcer area in patients with chronic venous leg ulcers compared to a standard antimicrobial dressing.
April 2018 in “Journal of Investigative Dermatology” This study found that in laboratory settings, dermal papilla cells cultured as spheroids showed significantly higher hair inductive potential and angiogenic factor expression compared to monolayer cultures.
17 citations
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January 2025 in “Journal of Nanobiotechnology” This review discusses the potential of bacterial extracellular vesicles in regenerative medicine, highlighting their advantages in addressing current EV challenges, and provides strategies for optimizing their preparation; it reports no new clinical results.
13 citations
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September 2016 in “Journal of Cellular Biochemistry” This study found that under hypoxic conditions, hair follicle-associated pluripotent stem cells differentiated into cardiac muscle cells at a higher rate compared to normoxic conditions.