Single-Cell Analysis Reveals Distinct Functional Heterogeneity of CD34+ Cells in Anagen and Diabetic Wounds

    Jia He, Wenting Huang, Jingru Wang … Xusheng Wang
    Studysummary This study investigated the heterogeneity of CD34+ cells in wound healing, identifying distinct cell clusters and suggesting potential therapeutic approaches for anagen and diabetic wounds.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on sciencedirect.com →
    Discuss this study in the Community →

    Research cited in this study 9

    1. Beta-Catenin Signaling Evokes Hair Follicle Senescence by Accelerating the Differentiation of Hair Follicle Mesenchymal Progenitors Frontiers in Cell and Developmental Biology · 2022
    2. Cellular Heterogeneity and Plasticity of Skin Epithelial Cells in Wound Healing and Tumorigenesis Stem cell reviews and reports · 2022
    3. Functional Hair Follicle Regeneration: An Updated Review Signal Transduction and Targeted Therapy · 2021
    4. Single-Cell Analysis Reveals Fibroblast Heterogeneity and Myeloid-Derived Adipocyte Progenitors in Murine Skin Wounds Nature Communications · 2019
    5. Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations During Wound Healing Cell Reports · 2018
    6. Lineage Identity and Location Within the Dermis Determine the Function of Papillary and Reticular Fibroblasts in Human Skin Journal of Investigative Dermatology · 2018
    7. SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin Journal of Investigative Dermatology · 2018
    8. Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin Cold Spring Harbor Perspectives in Medicine · 2014
    9. Perivascular Hair Follicle Stem Cells Associate With a Venule Annulus Journal of Investigative Dermatology · 2013

    Related research 2

    1. Single-Cell Analysis Reveals Distinct Functional Heterogeneity of CD34+ Cells in Anagen and Diabetic Wounds Biochemical and Biophysical Research Communications · 2022
    2. Wound Healing in Aged Skin Exhibits Systems-Level Alterations in Cellular Composition and Cell-Cell Communication Journal of Investigative Dermatology · 2022