TLDR Fat tissue extract may help treat vitiligo by reducing cell stress and promoting skin repair.
The document from June 1, 2019, reports on a study exploring the potential of adipose tissue extracellular fraction (AT-Ex) as a treatment for vitiligo. The study demonstrated that AT-Ex could improve the ability of vitiligo cells to combat oxidative stress, enhance cell proliferation, and activate skin regeneration pathways. AT-Ex was found to stimulate intracellular antioxidant enzymes, inactivate GSK3ß, and activate the Wnt/ß-catenin pathway. The study involved AT-Ex from 14 donors and included skin biopsies and cell cultures from 13 vitiligo patients and 17 healthy individuals. The findings suggest that AT-Ex could be an effective standalone therapy or an adjunct to cell transplantation therapies for vitiligo.
39 citations
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March 2017 in “Dermatologic clinics” UV light can help stimulate the growth of new pigment cells from hair follicles in people with vitiligo.
21 citations
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February 2017 in “Dermatologic surgery” Different techniques for vitiligo treatment work similarly well, with some better for specific body areas.
45 citations
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April 2016 in “Journal of Dermatological Science” The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
73 citations
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January 2013 in “European journal of dermatology/EJD. European journal of dermatology” Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.
8 citations
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July 2022 in “International Journal of Molecular Sciences” Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.
13 citations
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February 2023 in “Aging” A substance from hair follicle stem cells helps heal skin wounds in diabetic mice by promoting cell growth and preventing cell death.
27 citations
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January 2020 in “Experimental Dermatology” Immune cells affect hair growth and could lead to new hair loss treatments.
July 2023 in “International Journal of Molecular Sciences” N,N-Dimethylglycine Sodium Salt helps reduce skin inflammation and improves skin cell growth and healing.
15 citations
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February 2015 in “Han-gug chugsan sigpum hag-hoeji/Korean journal for food science of animal resources” Egg shell membrane hydrolysates can reduce wrinkles and improve skin health.
2 citations
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October 2015 in “Human Gene Therapy” The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
