Oxidative Stress and Autoimmune Skin Disease

The document discusses the role of antioxidants in combating oxidative stress, which is caused by an excess of free radicals and peroxides and can lead to various health issues. The skin is particularly vulnerable to oxidative stress from both internal and external sources. The paper explores the potential connection between oxidative stress and autoimmune skin diseases, whose pathophysiology is often not fully understood. It reviews current research on the relationship between oxidative stress and specific autoimmune skin conditions such as alopecia areata, pemphigus vulgaris, vitiligo, and psoriasis. The document also proposes potential directions for future studies and treatment options, although it indicates that the success of these investigations has been mixed.