Directing Rat Hair Follicle Stem Cells Toward Neuronal Lineage With Enhanced Trophic Factor Expression

    September 2024 in “ Advanced Biomedical Research ”
    Sareh Pandamooz, Sara Chavoshinezhad, Mandana Mostaghel … Mohammad Saied Salehi
    Studysummary In this study, chick embryo extract enhanced neuronal differentiation and trophic factor expression in rat hair follicle stem cells, suggesting potential improvements for stem cell therapies in neurodegenerative diseases.
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    Research cited in this study 12

    1. Local and Systemic Mechanisms That Control the Hair Follicle Stem Cell Niche Nature Reviews Molecular Cell Biology · 2023
    2. Oxytocin Receptor Expression in Hair Follicle Stem Cells: A Promising Model for Biological and Therapeutic Discovery in Neuropsychiatric Disorders Stem cell reviews and reports · 2023
    3. The Beneficial Effects of Chick Embryo Extract Preconditioning on Hair Follicle Stem Cells: A Promising Strategy to Generate Schwann Cells Cell proliferation · 2023
    4. Therapeutic Potential of Hair Follicle-Derived Stem Cell Intranasal Transplantation in a Rat Model of Ischemic Stroke BMC neuroscience · 2022
    5. Transplanted Hair Follicle Stem Cells Migrate to the Penumbra and Express Neural Markers in a Rat Model of Cerebral Ischemia/Reperfusion Stem Cell Research & Therapy · 2020
    6. Differentiation of Nestin-Negative Human Hair Follicle Outer Root Sheath Cells Into Neurons In Vitro Molecular Medicine Reports · 2017
    7. Cryopreservation of Hair-Follicle Associated Pluripotent Stem Cells Maintains Differentiation and Hair-Growth Potential Advances in experimental medicine and biology · 2016
    8. Hair Follicle Stem Cells: In Vitro and In Vivo Neural Differentiation World journal of stem cells · 2015
    9. Human Epidermal Neural Crest Stem Cells as Candidates for Cell-Based Therapies, Disease Modeling, and Drug Discovery Birth defects research · 2014
    10. Canine Epidermal Neural Crest Stem Cells: Characterization and Potential as Therapy Candidate for a Large Animal Model of Spinal Cord Injury Stem Cells Translational Medicine · 2014
    11. Mouse Epidermal Neural Crest Stem Cell (EPI-NCSC) Cultures Journal of Visualized Experiments · 2008
    12. Multipotent Nestin-Positive, Keratin-Negative Hair-Follicle Bulge Stem Cells Can Form Neurons Proceedings of the National Academy of Sciences · 2005