Mouse Epidermal Neural Crest Stem Cell (EPI-NCSC) Cultures

    Maya Sieber‐Blum, Yaofei Hu
    TLDR Mouse epidermal neural crest stem cells can become various cell types and are easily obtained from hair follicles.
    Mouse Epidermal Neural Crest Stem Cells (EPI-NCSC) were multipotent stem cells located in the bulge of hair follicles, capable of differentiating into various cell types such as neurons, nerve supporting cells, smooth muscle cells, bone/cartilage cells, and melanocytes. These cells were easily accessible from the hairy skin and could be isolated as a pure population. The document detailed a protocol for preparing EPI-NCSC cultures from mouse whisker follicles, involving the removal and dissection of whisker follicles, followed by the extraction of the bulge region for culture. EPI-NCSC began to emigrate from the bulge explants within 3 to 4 days.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 80 results

    Related Research

    1 / 1 results