Mouse Epidermal Neural Crest Stem Cell (EPI-NCSC) Cultures

May 2008 in “ Journal of Visualized Experiments ”

Maya Sieber‐Blum, Yaofei Hu

Epidermal Neural Crest Stem Cells EPI-NCSC hair follicles bulge region melanocytes

TLDR Mouse epidermal neural crest stem cells can become various cell types and are easily obtained from hair follicles.

The document described a method for isolating mouse epidermal neural crest stem cells (EPI-NCSC) from whisker follicles. These cells, remnants of the embryonic neural crest, were located in the bulge of hair follicles and were multipotent, capable of differentiating into various cell types such as neurons and melanocytes. The isolation process involved micro-dissecting whisker follicles from adult mice, with younger mice yielding more cells. EPI-NCSC were noted for their potential in cell replacement therapies and regenerative medicine, having been tested in a mouse model of spinal cord injury. The study highlighted the cells' migratory ability and potential applications in biomedical engineering.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community 9months progress fin/derma pen/minoxidil

in Progress Pictures 1000 upvotes 5 years ago

A user's 9 month progress using Finasteride, Derma Pen/Roller and Minoxidil to treat hair loss. Replies in the conversation include advice on topical application of Minoxidil and Dutasteride for regrowth and hair thickness.

community DIY treatment... Shedding completely stopped after 1.5 yrs

in Treatment 250 upvotes 3 years ago

Vitamin C mixed with shampoo stopped shedding and promoted hair regrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.

community Clearing the air on how non-surgical treatments really work

17 upvotes 6 years ago

Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.

community Is tazarotene potentially better than tretinoin in combination with topical minoxidil?

in Chat 1 upvotes 1 month ago

Tazarotene may be more effective than tretinoin when combined with topical minoxidil for hair loss due to its selective binding to RAR-beta and gamma, though it can cause irritation. Tazarotene's potency can lead to indirect inflammatory reactions despite potentially causing less irritation than tretinoin.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

in Research/Science 210 upvotes 1 year ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

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research Tracking Adult Stem Cells

180 citations , January 2011 in “EMBO Reports”