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GlossaryNeurotrophins (Neurotrophic Factors)

proteins that support neuron growth, survival, and function

Neurotrophins are a family of proteins that play a crucial role in the growth, survival, and maintenance of neurons, which are the cells responsible for transmitting information in the nervous system. They help support the health of nerve cells and are involved in processes like learning and memory. For professionals, key members of this family include nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF).

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GDNF Neurotrophic Factor Signaling Determines the Fate of Dermal Fibroblasts in Wound-Induced Hair Neogenesis and Skin Regeneration

research GDNF Neurotrophic Factor Signaling Determines the Fate of Dermal Fibroblasts in Wound-Induced Hair Neogenesis and Skin Regeneration

2 citations, January 2022 in “Experimental Dermatology”

GDNF signaling helps in hair growth and skin healing after a wound.

Psychological Stress Impact on Neurotrophic Factor Levels in Patients With Androgenetic Alopecia and Correlation With Disease Progression

research Psychological Stress Impact on Neurotrophic Factor Levels in Patients With Androgenetic Alopecia and Correlation With Disease Progression

October 2024 in “World Journal of Psychiatry”

Stress worsens hair loss in androgenetic alopecia.

research Regeneration of Skin Appendages and Nerves: Current Status and Further Challenges

71 citations, February 2020 in “Journal of Translational Medicine”

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

research Human Epidermal Neural Crest Stem Cells as a Source of Schwann Cells

44 citations, January 2015 in “Development”

Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.

research Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells

10 citations, January 2014 in “BioMed research international”

Rat whisker cells can help turn other cells into nerve cells and might be used to treat brain injuries or diseases.

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community Possible topical option for preventing BDNF-related hair loss

in Research/Science 7 upvotes 1 year ago

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.