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GlossaryNeural Differentiation

process where stem cells become specialized nerve cells

Neural differentiation, also known as neuronal differentiation, is the process by which stem cells or progenitor cells develop into specialized nerve cells, or neurons. This involves a series of genetic and biochemical changes that enable these cells to acquire the unique structures and functions necessary for transmitting nerve impulses and forming complex neural networks.

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research Abnormal Neuronal Differentiation and Mitochondrial Dysfunction in Hair Follicle-Derived Induced Pluripotent Stem Cells of Schizophrenia Patients

198 citations, June 2013 in “Molecular psychiatry”

Schizophrenia patients' stem cells show abnormal neuron development and mitochondrial issues.

research Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells

10 citations, January 2014 in “BioMed research international”

Rat whisker cells can help turn other cells into nerve cells and might be used to treat brain injuries or diseases.

Combination of Media, Biomaterials, and Extracellular Matrix Proteins to Enhance the Differentiation of Neural Stem/Precursor Cells into Neurons

research Combination of Media, Biomaterials, and Extracellular Matrix Proteins to Enhance the Differentiation of Neural Stem/Precursor Cells into Neurons

25 citations, April 2012 in “Acta Biomaterialia”

Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.

research Hair Follicle Stem Cells: In Vitro and In Vivo Neural Differentiation

25 citations, January 2015 in “World journal of stem cells”

Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.

research New Substrates for Stem Cell Control

11 citations, May 2018 in “Philosophical Transactions of the Royal Society B”

New materials help control stem cell growth and specialization for medical applications.

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