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Glossary Nitric Oxide Synthase

enzyme producing nitric oxide for blood vessel dilation and more

Nitric Oxide Synthase (NOS) is an enzyme responsible for producing nitric oxide, a molecule that plays a crucial role in various physiological processes, including blood vessel dilation, immune response, and neurotransmission. There are three main types of NOS: endothelial (eNOS), neuronal (nNOS), and inducible (iNOS), each serving different functions in the body.

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research Assessment of Nitric Oxide Synthase Protein Level in the Scalp of Androgenetic Alopecia

November 2025 in “QJM”

This study found that in men with androgenetic alopecia, nitric oxide synthase protein expression was significantly higher at androgenetic sites compared to non-androgenetic sites or those of healthy controls, suggesting a possible role in hair follicle regulation.

research Effect of androgen on nitric oxide synthase positive neurons in the medial preoptic area

January 2003 in “Zhonghua shiyan waike zazhi”

This study found that androgen is essential for erectile function in rats, and suggests that its effects may be partly mediated through nitric oxide synthase positive neurons in the medial preoptic area.

research Improvement of Tissue Survival of Skin Flaps by 5α-Reductase Inhibitors: Possible Involvement of Nitric Oxide and Inducible Nitric Oxide Synthase

1 citations , February 2015 in “PubMed”

This study found that azelaic acid and finasteride significantly increased iNOS expression and nitric oxide levels, which was associated with improved survival of skin flap grafts in rats.

research The expression of inducible nitric oxide synthase (iNOS) in the testis and epididymis of rats with a dihydrotestosterone (DHT) deficiency

28 citations , January 2009 in “Cellular & Molecular Biology Letters”

This study concluded that finasteride-induced DHT deficiency intensified constitutive iNOS expression in rat testicular and epididymal cells, suggesting a complex regulatory relationship needing further investigation.

research Nitric Oxide Signal Transduction and Its Role in Skin Sensitization

1 citations , June 2023 in “Biomolecules & therapeutics”

This article reviews the role of nitric oxide in skin health, including its influence on immune responses and potential therapeutic applications for contact dermatitis, but reports no new clinical results.

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community Finasteride Doubled my Total & Free Test but also my Estradiol - 8 months in

in Chat 32 upvotes 2 months ago

A 22-year-old male experienced increased testosterone and estradiol levels after 8 months on finasteride, leading to softer erections and reduced arousal. Suggestions included reducing finasteride dosage, using supplements like L-arginine, L-citrulline, zinc, and possibly tadalafil to improve symptoms.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

2 upvotes 1 year ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

in Research 413 upvotes 1 year ago

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

community Is ED after taking Fin or Dut caused by less DHT or an increase in Estrogen/Estradiol

3 upvotes 2 years ago

Finasteride and dutasteride may cause erectile dysfunction due to reduced DHT, affecting nitric oxide and sexual function. Some suggest using aromatase inhibitors to address side effects, while others believe individual sensitivity to DHT reduction varies.

community Could l-arginine be making hairloss worse?

5 upvotes 8 years ago

L-arginine may worsen hair loss by potentially increasing testosterone levels, especially in those with a DHT-sensitive gene. Users discuss the effects of increased nitric oxide on hair loss and consider stopping supplements like zinc and l-arginine to see if hair conditions improve.

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