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In this study, 17β-estradiol increased VEGF production in differentiated THP-1 cells, while dihydrotestosterone counteracted this effect by modulating adenylate cyclase activity.

The researchers reported that VEGF increases vascular permeability in mesenteric microvessels of anaesthetized frogs through specific cellular pathways involving tyrosine autophosphorylation and PLC activation.

In this animal study, rats treated with recombinant human growth hormone (at both low and high doses) experienced quicker burn wound healing than controls, with increased micro vessel density and altered expression of vascular endothelial growth factor, alongside changes in oxidative stress and inflammation markers.

This study reports that beta-glucan hybrid hydrogels, reinforced with laponite nanoclay, showed promising results in rat models for managing hemorrhage and diabetic wound healing by enhancing hemostasis, reducing inflammation, and promoting faster wound closure and tissue regeneration.

This study found that simvastatin interfered with insulin-induced VEGF expression and keratinocyte proliferation during skin repair in mice, effects that could be reversed by mevalonate.

This study found that dermal papilla cells in human hair follicles exhibit stronger expression of VEGF mRNA and protein compared to other follicular cells, suggesting their key role in angiogenic processes related to hair growth.

This review discusses the cyclical phases of hair follicle transformation and the various factors that regulate hair growth, reporting no new clinical results.

This study found that VEGF expression and microvessel density in hair follicles of Liaoning cashmere goats follow a bimodal pattern correlated with hair development throughout the year.

This study suggests that type IV collagenases, MMP-2 and MMP-9, play important roles in the hair cycle by regulating the expression of VEGF, IGF-1, and TGF-β in mice.

This study found that the type IV collagenases, MMP-2 and MMP-9, play significant roles in the hair cycle, potentially through their influence on VEGF, IGF-1, and TGF-β expression.

In this animal study, researchers observed that ginsenoside CK significantly reduced hair loss, improved sexual organ health, and encouraged hair growth in mice with androgenetic alopecia by modulating key signaling pathways and normalizing hormone metabolism, highlighting its potential as a therapeutic agent.

This study found that patients with psoriasis had a significantly higher prevalence of autoimmune diseases and other comorbidities compared to individuals without psoriasis.

This study found that the extract of Asiasari radix may promote hair growth in mice by enhancing protein synthesis, cell proliferation, and growth factor expression.

This research found that escin, when applied topically, enhances blood flow in human skin and promotes changes in endothelial cell signaling pathways, suggesting potential benefits for improving cutaneous microcirculation.

This study found that extracts from heterotropic cultures of Scenedesmus deserticola JD052 enhanced hair-inductive properties in human dermal papilla cells more effectively than photoautotrophic extracts, likely through activation of AKT/β-catenin signaling, despite similar loliolide content.

This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.

This study found that depletion of KRT17 in endometrial cancer reduced cell growth, motility, and angiogenesis, suggesting KRT17 as a potential therapeutic target.

In this study, topical application of Korean maritime pine bark extract at 2% concentration significantly promoted hair growth in mice, suggesting its potential use for hair loss prevention or treatment.

In this study, Gardenia florida fruit extract promoted hair growth in vitro and in vivo by enhancing hair growth-promoting gene expression and increasing hair follicle number, size, and depth in mice.

This study suggests that oleanolic acid may promote hair growth in mice with testosterone-induced androgenetic alopecia by activating the Wnt/β-catenin pathway and influencing various molecular levels.

Among in vitro and in vivo models, this study found that Miscanthus sinensis var. purpurascens flower extract may promote hair growth, potentially by modulating growth factor expressions and facilitating earlier hair follicle transitions in treated mice.

In this study, naked mole-rats demonstrated unique skin and hair follicle innervation features compared to other species, suggesting adaptations to their subterranean environment and poikilothermy.

This chapter discusses various skin functions and structures involved in protection, immune response, and homeostasis, but it reports no new research findings.

This review explores the potential link between psoriasis and metabolic syndrome, focusing on how disturbances in growth factors may connect these conditions and contribute to symptoms like keratinocyte proliferation and inflammation.

In this laboratory study, researchers observed that mouse vascular endothelial cells exhibit dynamic changes after exposure to ionizing radiation, including a transient endothelial subpopulation that facilitates vascular-epidermal communication and skin repair, with shifting roles in angiogenesis and immune surveillance over time.

This review discusses the roles of various growth factors and cytokines in skin regeneration, highlighting their potential for future therapeutic development, and reports no new experimental findings.

In this study, researchers identified a number of differentially expressed genes that may influence wool growth in Aohan fine wool sheep, offering insight into the genetic regulation of wool quality and yield.

This study found that thrombospondin-1 plays a critical role in hair follicle cycle regulation, with deficiency prolonging follicle growth and overexpression delaying it through antiangiogenic effects.

This study found that C. obtusa oils promoted hair growth in shaved mice and increased the expression of a hair growth regulator, VEGF, in a cell line.

This study found that uric acid-linked microvascular dysfunction may play a role in alopecia areata, suggesting that targeting endothelial function and uric acid regulation could be a potential management strategy.