Effects of Oleanolic Acid on Hair Growth in Mouse Dorsal Skin Mediated via Regulation of Inflammatory Cytokines

    March 2023 in “ Journal of Applied Biomedicine ”
    Bing Zhang, Wenyun Zhang, Jianfang Luo … Tinggang He
    Studysummary This study suggests that oleanolic acid may promote hair growth in mice with testosterone-induced androgenetic alopecia by activating the Wnt/β-catenin pathway and influencing various molecular levels.
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    Research cited in this study 19

    1. Hormonal Effects on Hair Follicles International journal of molecular sciences · 2020
    2. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy International Journal of Molecular Sciences · 2020
    3. Study on the Chemical Constituents of Nut Oil from Prunus Mira Koehne and the Mechanism of Promoting Hair Growth Journal of ethnopharmacology · 2020
    4. Effects of AiQingHua Oil on Microcirculation Disturbance and Alopecia in Mice Models Journal of King Saud University. Science/Maǧallaẗ ǧāmiʹaẗ al-malik Saʹūd. al-ʹUlūm · 2020
    5. Efficacy of Different Concentrations of Intralesional Triamcinolone Acetonide for Alopecia Areata: A Systematic Review and Meta-Analysis Journal of the American Academy of Dermatology · 2019
    6. Learning From Success and Failure: Biologics for Non-Approved Skin Diseases Frontiers in immunology · 2019
    7. Hair Regenerative Effect of Silk Fibroin Hydrogel with Incorporation of FGF-2-Liposome and Its Potential Mechanism in Mice with Testosterone-Induced Alopecia Areata Journal of Drug Delivery Science and Technology · 2018
    8. Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms International Journal of Molecular Sciences · 2018
    9. Naturally Occurring Hair Growth Peptide: Water-Soluble Chicken Egg Yolk Peptides Stimulate Hair Growth Through Induction of Vascular Endothelial Growth Factor Production Journal of Medicinal Food · 2018
    10. Hair Growth Promotion Effect of Cedrol Cream and Its Dermatopharmacokinetics RSC Advances · 2018
    11. Low-Level Laser Therapy for the Treatment of Androgenic Alopecia: A Review Lasers in Medical Science · 2017
    12. Alopecia Areata: Treatment Options and Efficacy Journal of the American Academy of Dermatology · 2017
    13. Beta-Catenin Is Involved in Oleanolic Acid-Dependent Promotion of Proliferation in Human Hair Matrix Cells in an In Vitro Organ Culture Model Fitoterapia · 2017
    14. Androgenetic Alopecia: A Review Endocrine · 2017
    15. Inhibitory Activities of Some Traditional Chinese Herbs Against Testosterone 5α-Reductase and Effects of Cacumen Platycladi on Hair Regrowth in Testosterone-Treated Mice Journal of Ethnopharmacology · 2015
    16. The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells Journal of Investigative Dermatology · 2015
    17. The Androgenic Alopecia Protective Effects of Forsythiaside-A and the Molecular Regulation in a Mouse Model Phytotherapy Research · 2015
    18. Loss of Memo, a Novel FGFR Regulator, Results in Reduced Lifespan The FASEB Journal · 2013
    19. Alopecia Areata: An Autoimmune Disease Causing Hair Loss The New England Journal of Medicine · 2012

    Related research 3

    1. The Molecular Mechanism of Natural Products Activating Wnt/Beta-Catenin Signaling Pathway for Improving Hair Loss Life · 2022
    2. Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss International Journal of Molecular Sciences · 2020
    3. Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways InTech eBooks · 2017