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    GlossaryWnt signaling pathway

    regulates cell growth and differentiation, crucial for hair regeneration

    The Wnt signaling pathway is a complex network of proteins that play a crucial role in regulating cell growth, development, and differentiation. It is particularly important in the context of hair growth and regeneration, as it influences the activity of hair follicle stem cells. Dysregulation of this pathway can lead to conditions like alopecia or other hair growth disorders.

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      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Estradiol

      an estrogen promoting hair regrowth more commonly used in women

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      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  140 upvotes 10 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.