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GlossaryWnt signaling pathway

regulates cell growth and differentiation, crucial for hair regeneration

The Wnt signaling pathway is a complex network of proteins that play a crucial role in regulating cell growth, development, and differentiation. It is particularly important in the context of hair growth and regeneration, as it influences the activity of hair follicle stem cells. Dysregulation of this pathway can lead to conditions like alopecia or other hair growth disorders.

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Escin Activates Canonical Wnt/Beta-Catenin Signaling Pathway by Facilitating the Proteasomal Degradation of Glycogen Synthase Kinase-3 Beta in Cultured Human Dermal Papilla Cells

research Escin Activates Canonical Wnt/Beta-Catenin Signaling Pathway by Facilitating the Proteasomal Degradation of Glycogen Synthase Kinase-3 Beta in Cultured Human Dermal Papilla Cells

July 2023 in “Current Issues in Molecular Biology”

Escin may help treat hair loss by boosting a specific cell growth pathway.

Baicalin Increases Hair Follicle Development by Enhancing Canonical Wnt/β-Catenin Signaling and Activating Dermal Papilla Cells in Mice

research Baicalin Increases Hair Follicle Development by Enhancing Canonical Wnt/β-Catenin Signaling and Activating Dermal Papilla Cells in Mice

23 citations, January 2018 in “International Journal of Molecular Medicine”

Baicalin helps hair growth by activating specific cell signals and pathways.

research Non-Canonical Wnt Signaling Promotes Directed Migration of Intestinal Stem Cells to Sites of Injury

September 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

Special gut cells help stem cells move to and fix injured areas by activating a specific signaling pathway.

research Canonical and Non-Canonical Wnt Signaling Control the Regeneration of Amputated Rodent Vibrissae Follicles

5 citations, January 2016 in “Journal of Molecular Histology”

Both main and alternative Wnt signaling are important for regrowing rodent whisker follicles.

research The Roles of WNT Signaling Pathways in Skin Development and Mechanical-Stretch-Induced Skin Regeneration

2 citations, November 2023 in “Biomolecules”

WNT signaling is crucial for skin development and healing.

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community The Real Cause Of Androgenetic Alopecia

in Research/Science 667 upvotes 1 month ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community JW Pharmaceutical shows superiority of 'JW0061' in hair growth over existing treatments in US

in Research/Science 99 upvotes 6 months ago

JW0061 shows superior hair growth results compared to existing treatments, with significant increases in hair follicles. The Wnt/β-catenin pathway is crucial for hair growth, and JW0061 activates this pathway effectively.

community Back again with a 17 month update. (Fin/Min doing the heavy lifting, occasional 0.5mm microneedling, and Nizoral for scalp health) - Angles are not identical but whatever - Expecting and hoping to be back to pre-hairloss hairline within 6 months from now.

in Progress Pictures 393 upvotes 9 months ago

The conversation is about a user's 17-month progress in treating hair loss using finasteride, minoxidil, occasional 0.5mm microneedling, and Nizoral. The user reports significant hairline recovery and aims to achieve a pre-hair loss hairline within the next 6 months.

community Seems like good progress... Happy with it so far

in Progress Pictures 219 upvotes 1 year ago

The user "Segggs" shared their progress with hair loss treatments including 6 months of foam minoxidil, 3 months of finasteride, keto shampoo, and inconsistent microneedling. The replies were positive, with some users commenting on the regrowth in the temple area.

community [20M]What 8 months of no progress looks and feels like on fin/min/derma.

in Finasteride/Dutasteride 8 upvotes 7 months ago

A 20-year-old has seen no improvement in hair loss after 8 months using finasteride, minoxidil, topical solutions, and microneedling. They express frustration and a loss of confidence due to the lack of results.

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