research Slow Progress in Prostate Cancer
Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.
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research Targeting the Pre-Receptor Metabolism of Cortisol as a Novel Therapy in Obesity and Diabetes
Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.
research 5α-Reductase Activity in the Prostate
Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
research Clinical Biochemistry of Dihydrotestosterone
Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
research Expression of Steroidogenic Enzymes in Human Sebaceous Glands
Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Type 2 Diabetes
Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
research The Cardiovascular Safety of Dutasteride
Dutasteride is as safe for the heart as finasteride.
research Mechanisms of Disease: Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 as a Novel Treatment for Metabolic Syndrome
Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
research Effects of Flavonoid Derivatives on Human Microvascular Endothelial Cells
Some flavonoids may help with hair growth by affecting blood vessel function in hair follicles.
research Characteristic Localization of Neuronatin in Rat Testis, Hair Follicle, Tongue, and Pancreas
Neuronatin is found in specific cells within rat testis, hair follicles, tongue, and pancreas, suggesting it has various roles in tissue development and function.
research Female Pattern Hair Loss: Current Treatment Concepts
Minoxidil 2% and 5% are common treatments for female pattern hair loss, with other options including anti-androgens, oral contraceptives, and hair transplantation.
research Effects of 5-Alpha Reductase Inhibitors
5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.
research The Role of Dutasteride in the Treatment of Benign Prostatic Obstruction and Related Conditions
Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research 5α-Reduced Glucocorticoids: A Story of Natural Selection
Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
research Cardiovascular Profile of Pharmacological Agents Used for the Management of Polycystic Ovary Syndrome
Medications for PCOS don't seem to raise heart disease risk.
research In Vitro 5α-Reductase Inhibition by Selected Ayurvedic Herbs for Androgenic Disorders
Emblica officinalis and Eclipta alba may help treat hair loss naturally.
research The 5α-Reductase Inhibitor Finasteride Is Not Associated With Alterations in Sleep Spindles in Men Referred for Polysomnography
Finasteride doesn't affect sleep spindles in men.
research Health Promotion Potential of Vegetables Cultivated in Northern Thailand: A Preliminary Screening of Tannin and Flavonoid Contents, 5α-Reductase Inhibition, Astringent Activity, and Antioxidant Activities
Some vegetables from Northern Thailand show promise for health benefits, including hair loss treatment and antioxidant properties.
research A Population-Based Study of the Risk of Osteoporosis and Fracture with Dutasteride and Finasteride
Dutasteride and finasteride have similar risk for osteoporosis and fractures in older men.
research Cholesterol Homeostasis: Links to Hair Follicle Biology and Hair Disorders
Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
research Pathogenesis of Androgenetic Alopecia
Androgenetic alopecia, or hair loss, is caused by a mix of genetics, hormones, and environment, where testosterone affects hair growth and causes hair to become smaller and grow for a shorter time.
research Androgen Biosynthesis and Gene Defects
Gene mutations can cause problems in male genital development.
research Androgenetic, Diffuse, and Senescent Alopecia in Men: Practical Evaluation and Management
The conclusion is that treatments like finasteride and minoxidil can prevent baldness progression and improve hair density, but more research is needed on other therapies.
research Evaluating 5 Alpha Reductase Inhibitors for the Treatment of Male Androgenic Alopecia
Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.
research Cutaneous Androgen Metabolism: Basic Research And Clinical Perspectives
Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
research Determination of Finasteride, Indapamide, and Tiemonium Methyl Sulphate Using Surface Plasmon Resonance Band of Silver Nanoparticles
research Androgenetic Alopecia: Overview, Epidemiology, Pathophysiology, and Treatment
Various treatments exist for hair loss, but more research is needed for better options.
research Dermatologic Manifestations of Polycystic Ovary Syndrome
Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.
research The Vitamin B5/Coenzyme A Axis: A Target for Immunomodulation?
Vitamin B5 and coenzyme A may help regulate the immune system and could improve treatments for chronic diseases and cancer.