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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Rats had lasting erectile problems after stopping a certain medication.

Finasteride negatively affects fish reproduction and gonadal development.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Finasteride may help some women with hair loss, but better options exist.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Finasteride effectively and safely treats recurrent priapism in children and adolescents with sickle cell disease.

Spanish experts provided guidelines for treating skin side effects in cancer patients on new therapies, stressing early action and teamwork.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Taking tadalafil and finasteride together is safe and effective for treating urinary symptoms and erectile dysfunction in men with enlarged prostates.

A reliable method was developed to measure dutasteride in tablets accurately and consistently.

Sebocytes play a key role in controlling androgen levels in human skin.

Finasteride effectively treats male hair loss, improving growth and density.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Akt2 protein is essential for normal cell division in early mouse embryos.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

Finasteride improves hair growth in men with androgenetic alopecia.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

CXXC5 can both suppress and promote cancer, making it a complex target for treatment.