Evidence for the Efficacy and Safety of Tadalafil and Finasteride in Combination for the Treatment of Lower Urinary Tract Symptoms and Erectile Dysfunction in Men with Benign Prostatic Hyperplasia

The study concluded that combining tadalafil and finasteride was a safe and effective treatment for lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) in men with benign prostatic hyperplasia (BPH). Involving 696 participants, the combination therapy significantly improved both LUTS and ED compared to monotherapy, with greater reductions in IPSS scores and higher IIEF-EF scores over 26 weeks. The treatment was well-tolerated, with a lower incidence of sexually related adverse events, making it an attractive option for men with BPH and ED.