7 citations
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September 2021 in “Antimicrobial Agents and Chemotherapy” This study found that olorofim demonstrated potent in vitro and in vivo antifungal activity against dermatophytes, resolving skin lesions in a guinea pig model similar to clotrimazole, suggesting it may be a promising treatment for dermatophytosis.
9 citations
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January 2013 in “Acta dermato-venereologica” The conclusion is that "trichoknesis" should be recognized as a separate condition from trichodynia, characterized by itching instead of pain.
July 2026 in “International Journal of Research in Pharmacology & Pharmacotherapeutics” In this study, the methanolic extract of Tridax procumbens Linn demonstrated significant antiulcer activity in a mice model of acetic acid-induced ulcerative colitis, offering 57.12% ulcer protection compared to 50.60% by the standard drug prednisolone.
24 citations
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June 2020 in “Dermatologic Therapy” This review discusses recent advances in the pharmacological treatment of trichotillomania, highlighting potential benefits of glutamate-modulating agents, and reports no new clinical results.
9 citations
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June 2017 in “Pharmacological Reports” This study found that ATP-sensitive potassium channels may play a role in chloroquine-induced itching in mice, as channel openers reduced scratching behavior while a blocker reversed these effects.
March 2026 in “Preprints.org” In this study, plerixafor was found to enhance melanogenesis and promote repigmentation by engaging a β-arrestin–β-catenin–MITF signaling axis in melanocytes, and showed effectiveness in restoring depigmentation in a murine model without causing systemic toxicity.
7 citations
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October 2012 in “PubMed” This study found that intralesional triamcinolone was more effective than topical anthralin in promoting hair regrowth in alopecia areata patients, but it also had a higher relapse rate.
March 2025 in “Molecules” This study explored the in vitro skin penetration of two compounds from Tectona grandis leaf extract used for standardization and found that compound 1 penetrates more efficiently than compound 2, especially with a propylene glycol enhancer.
July 2026 in “Free Radical Biology and Medicine”
November 2022 in “Journal of Investigative Dermatology” This study found that in mouse melanocytes, the cytoplasmic dynein complex component Dynlt3 is necessary for proper melanosome transport, acidity regulation, and effective transfer to keratinocytes, linking it to skin pigmentation processes.
66 citations
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July 2010 in “Journal of Proteome Research” This study suggests that an immune response to trichohyalin and keratin 16 may contribute to the pathogenesis of alopecia areata.
May 2022 in “Experimental dermatology” In this study, hair shafts from trichothiodystrophy patients with ERCC2 mutations revealed abnormal cuticle structures and protein imbalances compared to normal hair shafts.
January 2024 in “Figshare” This study concluded that an ointment containing pine turpentine oil, larch turpentine, and eucalyptus oil was an effective and safe treatment for folliculitis, showing improvement over placebo in lesion evolution, responder rate, and patient assessment.
November 2025 in “Frontiers in Veterinary Science” In this study, feeding H-line chickens a diet with 1.0% tyrosine for 40 days significantly increased melanin deposition in feathers and revealed changes in gene expression related to melanin pathways, suggesting tyrosine's involvement in regulating feather color through the EDNRB2 regulatory network.
December 2025 in “Molecular Pain” This study identified that the MC-5-HT-HTR2A axis plays a role in chronic pruritus in a mouse model of SADBE-induced allergic contact dermatitis, suggesting potential for therapeutic targeting.
July 2014 in “Americanae (AECID Library)” This study found that extracts from Tridax procumbens and Ouratea spectabilis reduced seed germination and inhibited root and hypocotyl growth in lettuce, indicating potential allelopathic effects.
June 2023 in “International Ayurvedic Medical Journal” This review article compiles extensive information on Tridax procumbens, an Ayurvedic herb, detailing its traditional uses, chemical makeup, and various pharmacological properties, including its roles in wound healing and as an antimicrobial agent.
49 citations
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November 2016 in “Frontiers in Pharmacology” This study found that over 26% of patients using Tripterygium wilfordii Hook F experienced adverse events, highlighting the need for better strategies to manage these risks.
September 2023 in “International journal of molecular sciences” In this study involving ICR mice, researchers found that Korean red pine bark extract improved cognitive functions impaired by TMT through mechanisms like antioxidant system protection, cholinergic and synaptic support, mitochondrial regulation, and reduction of neuro-inflammation and apoptosis.
April 2025 in “The Journal of Agriculture and Development” In this study, researchers optimized the extraction conditions for polyphenols from the medicinal herb Eclipta prostrata, achieving the highest polyphenol content under specific conditions of temperature, solvent concentration, and time, and found the extract to have significant antioxidant activity.
21 citations
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January 2000 in “Fetal Diagnosis and Therapy” This study found that trichothiodystrophy can be diagnosed prenatally in the second trimester using an endoscopically-guided fetal eyebrow biopsy, with sulfur content analysis being the most reliable test.
This study found that ethanol extract of fragrant pandanus leaves inhibited the growth of the dandruff-causing fungus Pityrosporum ovale, with higher concentrations showing greater inhibitory effects.
15 citations
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January 1988 Hair follicles have unique proteins that vary by species and are influenced by nutrition.
3 citations
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October 2018 in “Journal of cosmetic dermatology” This study found that intralesional pentoxifylline injections were effective for localized alopecia areata, with the best results observed when combined with triamcinolone acetonide.
37 citations
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January 2017 in “International Journal of Dermatology” This study found that trichoscopic features like exclamation mark hairs and angulated hairs were more indicative of alopecia areata in an Asian population, while features like broken hairs of different lengths and flame hairs were more common in trichotillomania.
8 citations
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July 2018 in “Analytical sciences” This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.
1 citations
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July 2024 in “Journal of Investigative Dermatology” TAK-279 effectively reduces psoriasis symptoms and is safe.
2 citations
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January 2018 in “International Journal of ChemTech Research” This study used phytochemical screening and FTIR spectroscopy with PCA to reveal slight chemical differences between two varieties of Eclipta alba, providing a method for their effective discrimination.
4 citations
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January 2024 in “Scientific Reports” Pumpkin seeds may help expel parasites, but findings are retracted.
161 citations
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June 1993 in “Journal of Biological Chemistry” This study suggests that human trichohyalin may function as a flexible rod linking keratin intermediate filaments and as a scaffold protein in hair follicle and epidermis cell envelopes.