Intralesional Pentoxifylline Injection in Localized Alopecia Areata

October 2018 in “ Journal of cosmetic dermatology ”

A.I. El-Taweel, E.M. Akl

pentoxifylline triamcinolone acetonide intralesional injections alopecia areata localized alopecia areata PTX TRA AA

From the encyclopedia

autoimmune disorder causing patchy hair loss

Studysummary This study found that intralesional pentoxifylline injections were effective for localized alopecia areata, with the best results observed when combined with triamcinolone acetonide.

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Research cited in this study

9 / 9 results

research Treatment Options for Alopecia

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research The Genetics Of Alopecia Areata: New Approaches, New Findings, New Treatments

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research Advances in the Management of Alopecia Areata

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research Histopathology of Alopecia Areata, Acute and Chronic: Why Is It Important to the Clinician?

43 citations , May 2011 in “Dermatologic Therapy”

This article discusses the phases and histological features of alopecia areata and reports no new clinical findings; the authors emphasize recognizing these phases for accurate diagnosis.

research Complementary And Alternative Medicine In Alopecia Areata

15 citations , December 2009 in “American journal of clinical dermatology”

The effectiveness of alternative treatments for alopecia areata is uncertain and needs more research.

research Treatment of Persistent Alopecia Areata with Sulfasalazine

45 citations , July 2008 in “International Journal of Dermatology”

This study found that oral sulfasalazine led to varying hair regrowth outcomes in patients with persistent alopecia areata, with 56.3% showing moderate to good responses.

research Interventions for Alopecia Areata

164 citations , April 2008 in “Cochrane library”

This review of interventions for alopecia areata found no significant treatment benefits for hair growth compared to placebo, indicating a need for larger, well-conducted studies.

research Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack

253 citations , December 2007 in “Journal of Investigative Dermatology”

This study suggests that human hair follicles may actively suppress natural killer cells, which contrasts with the observed defects in NK cell regulation in alopecia areata.

research Effect of Thioredoxin Reductase 1 on Glucocorticoid Receptor Activity in Human Outer Root Sheath Cells

34 citations , March 2007 in “Biochemical and Biophysical Research Communications”

This study suggests that decreased expression of thioredoxin reductase 1 in hair follicle cells may contribute to glucocorticoid resistance in some alopecia areata patients by affecting the intracellular redox system.