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Research

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research Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation.

409 citations , May 1991 in “Genes & Development”

This study observed that overexpression of TGF-alpha in transgenic mice led to thicker epidermis and stunted hair growth, particularly in regions with normally thick skin and low hair density.

Defining the Impact of Beta-Catenin/Tcf Transactivation on Epithelial Stem Cells

research Defining the impact of β-catenin/Tcf transactivation on epithelial stem cells

384 citations , June 2005 in “Genes & development”

This study found that stabilized beta-catenin is crucial for activating stem cell transition from quiescence to proliferation in hair follicles by influencing gene expression within the stem cell niche.

research Enhancing Permeation of Drug Molecules Across the Skin via Delivery in Nanocarriers: Novel Strategies for Effective Transdermal Applications

365 citations , March 2021 in “Frontiers in Bioengineering and Biotechnology”

This review discusses the potential of nanocarriers to enhance transdermal drug delivery and the combination of these carriers with physical methods, but it reports no new experimental results.

research Transient activation of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours

335 citations , March 2004 in “Development”

This study found that continuous β-catenin signaling in adult mouse epidermis can reprogram hair follicles to form benign tumors, which regress after the signaling is discontinued.

research 40nm, but not 750 or 1,500nm, Nanoparticles Enter Epidermal CD1a+ Cells after Transcutaneous Application on Human Skin

323 citations , April 2006 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that 40 nm nanoparticles can effectively penetrate into hair follicles and epidermal Langerhans cells in human skin samples, potentially enabling efficient transcutaneous vaccine delivery.

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Community Join

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community How much would the transplant cost

in Transplants 7 upvotes 3 weeks ago

The user has been using oral finasteride and minoxidil for 5-6 months to stop hair loss and is considering a hair transplant. It is suggested to wait 18-24 months for full effects before considering a transplant, with Turkey and Thailand mentioned as cheaper options.

community Is it time for a hair transplant?

in Transplants 5 upvotes 4 weeks ago

The conversation is about a person considering a hair transplant due to hairline recession, despite using minoxidil and finasteride. They are advised against a transplant for now and are exploring other treatments like microneedling and topical dutasteride due to medication interactions.

community Transplant and people with diabetes.

1 upvotes 4 weeks ago

The conversation discusses the experiences of individuals with type 1 or type 2 diabetes undergoing hair transplants, focusing on healing, A1C levels, and associated risks. It does not mention specific treatments like Minoxidil, finasteride, or RU58841.

community Transitioning from topical Fin to oral Fin: anything I should know?

5 upvotes 1 month ago

The conversation is about transitioning from topical to oral finasteride for hair loss treatment. Users suggest tapering off the topical while starting the oral dose, with some recommending using both simultaneously for a period.

community Am I a suitable candidate for a hair transplant?

in Transplants 8 upvotes 1 month ago

The user is considering a hair transplant due to thinning hair but has been using dutasteride and topical minoxidil for 4 years, which has stabilized and thickened their hair. They are advised to continue with current treatments and consider other options like microneedling, as transplants may not be ideal for diffuse thinning.

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Learn

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learn Transcutol P

learn Hair Transplant

Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.

Is a hair transplant permanent? Transplanted hair is generally permanent but requires ongoing care to maintain results.
Will transplanted hair fall out after a hair transplant? Transplanted hair is permanent but may temporarily shed before new growth occurs.
Does transplanted hair require special care? Transplanted hair generally requires no special care after initial healing.
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learn Castor oil

a traditional, natural remedy touted for promoting scalp health and hair growth

learn Verteporfin

chemical that might completely regrow follicles from hair transplant extractions

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Experts

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Clinics

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