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Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.

Mouse Notch is important for determining cell roles in hair follicles.

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

Dlx3 is essential for hair growth and regeneration.

Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.

Transamidases help form strong crosslinks in hair proteins, crucial for hair strength.

The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.

Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.

Future hair cosmetics will be safer and more effective.

CD8+ T cells are involved in alopecia areata and may cause disease relapse.

The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.

PAI-2 helps in the maturation and protection of hair and nail cells.

Alopecia areata is an incurable autoimmune condition causing hair loss, with research aiming for better treatments.

The Gsdma3 gene is essential for normal hair development in mice.

TGase 3 helps build hair structure by forming strong bonds between proteins.

The oncoprotein causes abnormal hair growth without increasing skin cancer risk.

Fat under the skin releases HGF which helps hair grow and gain color.

The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.

The hair cuticle is made of tough proteins that protect the hair, but more research is needed to fully understand its structure.

The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.

Clim proteins are essential for maintaining healthy corneas and hair follicles.

A mouse gene mutation increases the risk of skin cancer.

Citrullinated proteins from Porphyromonas gingivalis may contribute to rheumatoid arthritis.

A gene variant increases the risk of a type of hair loss by affecting hair protein production.

Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.

Hairless protein affects hair follicle structure by regulating the Dlx3 gene.

Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.

Oxidative stress plays a significant role in alopecia areata, and new treatments may include JAK inhibitors and antioxidants.

EGFR helps control how hair grows and forms without needing p53 protein.

A specific group of skin stem cells was found to help maintain hair follicle cells.