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This review discusses the use of derma rollers for cosmetic purposes and their potential in transdermal drug delivery by summarizing evidence on their design, efficacy, safety, and concerns from preclinical and clinical reports.

This study found that nano-sized minoxidil formulations significantly increased skin penetration and follicular drug delivery for alopecia areata treatment, compared to conventional ethanol-based solutions, and demonstrated effective controlled release over six hours.

This study found that 5% primed conditioned medium from human umbilical cord blood-derived mesenchymal stromal cells significantly improved hair density, thickness, and growth rate in patients with androgenetic alopecia.

This study found that using layer-by-layer encapsulation techniques on dermal papilla cells can support their function and may help treat hair loss when used in conjunction with freshly isolated epidermal cells.

This review discusses the topical use of systemic drugs for cutaneous disorders and reports a lack of strong evidence from randomized controlled trials, highlighting the need for larger comparative effectiveness studies.

Some chemicals absorbed through the skin can cause serious health problems.

This study concludes that phospholipid–polymer hybrid nanoparticles may be an effective delivery system for quercetin in treating androgenic alopecia by improving hair regrowth and preventing hair follicle cell apoptosis in rat models.

This study found that microneedling combined with calcipotriol plus betamethasone was more effective in treating vitiligo than microneedling with tacrolimus, particularly in difficult-to-treat areas.

This review highlights that transferosomes, or ultradeformable lipids, show promise for improving dermal delivery, exhibiting efficient drug transport across the skin's barrier and offering potential benefits for treating chronic skin disorders with better bioavailability.

This review discusses laser-assisted drug delivery for enhancing topical treatment efficacy in various dermatological and medical applications but reports no new clinical results, emphasizing the need for further research to optimize its use.

This study found that adapalene-loaded nanospheres in a hyaluronic acid gel enhanced skin penetration and were nonirritant, making them potentially suitable for treating acne on oily skin.

This study found that lipid nanocarriers called squarticles, conjugated with an antibody, enhanced minoxidil uptake in dermal papilla cells, potentially improving alopecia treatments.

This study found that PEGylation of nanoparticles enhances their penetration into hair follicles, with higher molecular weight PEG resulting in deeper follicular delivery.

This review discusses the multifaceted roles of hair follicles in skin health, including potential contributions to skin neoplasias, and reports no new results.

In this publication, a collaborative group reviewed the role of dermocosmetics in cancer care and formulated recommendations for using these products to manage skin toxicities and minimize treatment interruptions associated with cancer therapies.

In this ex vivo and mouse model study, Tofacitinib-loaded nanoparticles demonstrated enhanced delivery of the drug into hair follicles and reduced inflammatory effects compared to conventional forms, indicating potential for safer, topical use in treating alopecia areata.

This meta-analysis found that patients with androgenetic alopecia have significantly abnormal lipid profiles, which could contribute to the link between this condition and cardiovascular diseases.

This study found that men with early-onset androgenetic alopecia had a higher prevalence of metabolic syndrome and carotid atheromatous plaques than control subjects, suggesting a need for cardiovascular screening in this group.

This review discusses the therapeutic properties of polydeoxyribonucleotides derived from marine organisms for wound healing and inflammation, but it reports no new clinical results.

This study found that dual-frequency ultrasound with microbubble cavitation significantly enhanced minoxidil delivery and hair growth in both lab and animal models compared to single-frequency ultrasound, without damaging the skin in mice.

This study reported that a single local subcutaneous infusion of mesenchymal stromal cells from the human umbilical cord promoted wound healing, improved blood circulation, and reduced wound size in patients with chronic wounds without significant adverse effects over one year.

This study reported that microparticle-loaded emulsions containing caffeic acid achieved more homogeneous distribution and prolonged release in hair follicles, suggesting potential for effective folliculitis treatment.

This paper proposes a new hypothesis that androgenic hair loss may be caused by changes in scalp vasculature due to androgen effects, but reports no new experimental results.

This review derived guidelines for scalp surgery suggesting improved outcomes when avoiding neurovascular structures, preserving tissue integrity, and maintaining hair direction, but it reports no new clinical results.

This systematic review found inconclusive evidence on the effectiveness of botulinum toxin for treating alopecia and highlighted the need for further prospective randomized controlled trials.

This study demonstrated that minoxidil-encapsulated PLLGA nanoparticles significantly increased minoxidil delivery to hair follicles compared to a minoxidil aqueous solution in mice.

This review discusses the potential of evaluating hair follicle characteristics as early indicators of vascular impairment and organ damage in pre-diabetic individuals, but reports no new clinical results.

This review discusses the effects of vacuum massage on skin structures and concludes that there is insufficient evidence for its efficacy in treating burn scars, suggesting more research is needed on its potential benefits and mechanisms.

In this study, non-obese females with early-onset androgenetic alopecia showed higher total cholesterol, LDL cholesterol, triglycerides, and atherogenic index, and lower HDL cholesterol compared to controls, suggesting an association with adverse cardiovascular risk factors.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.