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Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Targeting the Smoothened receptor shows promise for treating certain cancers.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Variant G of the KRTAP20-1 gene improves wool curliness in Chinese Tan sheep.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Plant-derived extracellular vesicles show promise for treating diseases like cancer and inflammation.

Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.

A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.

Selecting specific KRTAP26-1 gene variants can improve wool quality in sheep.

Changthangi goats have specific genes that help produce Pashmina wool.

KAP7.1 and KAP8.2 genes are crucial for cashmere quality in goats.

New treatments targeting specific genes show promise for treating keratin disorders.

Metformin, usually used for diabetes, can also help treat hair loss from alopecia areata due to its ability to reduce inflammation and stimulate new hair growth.

PDF2 senses specific lipids and regulates root growth and gene expression in Arabidopsis.

Eating a balanced diet with specific nutrients can help manage menopause symptoms and prevent related health issues.

Epigenetic factors play a crucial role in skin health and disease.

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

Poplar seed hairs grow from the placenta at the ovary base, with endoreduplication playing a key role in their development, and share similar cellulose synthesis processes with cotton fibers.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.

A specific protein in chicken embryos links early skin layers to feather development.

A20 protein is crucial for normal skin and hair development.

Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.

Beta-HPV and MCPyV are linked to certain skin cancers, with ongoing research and vaccine development.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.

Certain RNA molecules are important for the development of wool follicles in sheep.