September 2023 in “Journal of the American Academy of Dermatology” Topical tofacitinib helped a man with severe scalp condition after other treatments failed.
This study observed that mesenchymal stem cell-conditioned medium accelerated burn wound healing in rats by enhancing epidermal growth factor presence, improving wound closure, collagen density, and re-epithelialization compared to the control.
This study found that while there are some ethnic differences in skin and hair follicle characteristics, these differences are unlikely to significantly affect the penetration of topical substances, suggesting other factors such as cultural habits may also play a role.
3 citations
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February 2021 in “Evidence-based Complementary and Alternative Medicine” This study observed that oral administration of BeauTop, a Chinese herbal medicine, significantly increased hair growth indicators, including VEGF expression, hair follicles, and hair coverage in C57BL/6 mice.
May 2020 in “Jurnal Penelitian Perawat Profesional” This literature review identified that katuk leaves, rich in vitamins and phenolic compounds, show potential in preventing hair loss by promoting hair growth, enhancing vascularity, and nourishing hair.
October 2022 in “Hair Transplantation” This article discusses the temporary scalp trichopigmentation procedure, detailing its unique approach compared to traditional scalp micropigmentation, and reports no new clinical findings.
May 2025 in “International Journal of Trichology” In this case report, a 7-year-old boy with alopecia totalis experienced significant hair regrowth after adding topical tofacitinib and mometasone to his treatment regimen, suggesting potential benefits of topical Janus kinase inhibitors for pediatric patients with this condition.
1 citations
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September 2024 in “IP Indian Journal of Clinical and Experimental Dermatology” This source discusses the potential of topical JAK inhibitors, like tofacitinib, as effective treatments for autoimmune skin diseases, emphasizing their superior safety profile and minimal adverse effects compared to conventional systemic therapies.
May 2020 in “Business Innovation & Entrepreneurship Journal” This study discusses the development of a turmeric-based herbal hair removal product named PASIKULA, highlighting its potential to increase the economic value of turmeric and acceptance by consumers.
January 2018 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” Scalp micropigmentation is a process where tiny dots of pigment are tattooed onto the scalp to create the appearance of a shaved head or fuller hair.
6 citations
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April 2023 in “Frontiers in Bioengineering and Biotechnology” In a murine burn wound model, this study found that an enhanced fractal self-pumping dressing significantly reduced wound area and tissue edema by efficiently draining excess exudates.
May 2023 in “Jurnal Kedokteran dan Kesehatan Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya” This case report concludes that while multivitamin, mineral, and herbal supplements are used in alopecia areata treatment, existing scientific evidence is insufficient for definitive clinical recommendations on their effectiveness.
In a study on female Wistar rats, researchers found that a hair tonic containing a 7.5%:2% combination of talok and pare leaf extracts increased hair growth comparable to minoxidil, showing similar efficacy in promoting hair growth without significant statistical difference.
March 2023 in “JIIS (Jurnal Ilmiah Ibnu Sina): ilmu farmasi dan kesehatan” This study concluded that the optimum biotin microemulsion hair tonic composition involves span 80 (20%), tween 80 (9.47%), and PEG 400 (5%), providing favorable viscosity and globule size.
January 2024 in “Jurnal Ilmiah Ibnu Sina (JIIS) Ilmu Farmasi dan Kesehatan” In this study, researchers developed a hair tonic using shallots (Allium cepa L.) and found that its F2 formulation was as effective as the positive control in promoting hair growth on the 21st day and remained stable over 28 weeks of testing.
1 citations
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January 2014 in “Jurnal Tata Rias” In this study, the hair tonic with a 3:3 avocado extract to honey ratio was most preferred by panelists and may be suitable for preventing hair loss.
7 citations
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April 2018 in “Molecular Medicine Reports” This study found that BeauTop, a supplement containing several traditional Chinese herbs, may promote hair growth in mice with alopecia, potentially by modulating EGF and FGF-7 levels.
1 citations
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October 2025 in “Ophthalmology Science” In this experimental study, researchers found that intravitreal injections of up to 100μg of topotecan in rabbits caused no systemic or ocular toxicity, while 200μg doses resulted in localized retinal changes and decreased electroretinography amplitudes near the injection site.
54 citations
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February 1994 in “Journal of Investigative Dermatology”
June 2024 in “Indian Dermatology Online Journal” In this study, 40% of alopecia areata patients using topical 2% tofacitinib ointment achieved greater than 50% improvement in hair regrowth after six months, showing significant efficacy compared to controls, with no serious adverse effects reported.
April 2025 in “Jurnal Analis Farmasi” This study evaluated hair tonic formulations containing Ambon banana peel extract and found that the preparation, particularly at an 8% concentration, significantly promoted hair growth compared to other formulations, though it still differed from the control group's effectiveness.
December 2021 in “Jurnal ilmiah Manuntung” This study tested a hair tonic containing gotu kola and garlic extracts on rabbits, finding that the formulation with 5% gotu kola and 0.04% garlic showed promising hair growth results and remained stable during storage.
2 citations
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October 2018 in “Archives of Dermatological Research” The researchers reported that topical tofacitinib in mice increased hair follicles in the growth phase and boosted noggin and BMP4 mRNA expressions, compared to a vehicle and minoxidil.
1 citations
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February 2015 in “Zenodo (CERN European Organization for Nuclear Research)” This study tested five different brands of hair building fibers, examining their electrostatic and dielectric properties as well as analyzing their fiber structure with scanning electron microscopy.
January 2016 in “Jurnal Farmasi Indonesia” In this study, hibiscus leaf extract hair tonic at 10% concentration showed better hair growth promotion activity compared to minoxidil 2% in a rabbit model, although it caused eye irritation.
This review, authored by Deirdre A. Buckley, explores key concepts in managing dermatological conditions through topical therapies, including formulation considerations, prescribing practices, and potential hazards associated with their use.
1 citations
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August 2019 In this study, a hair tonic formulation with 25% ethanol extract of mangkokan leaves showed effectiveness in promoting hair growth, as measured by significant differences in hair length and weight compared to the control.
131 citations
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October 2004 in “Clinical Cancer Research” This study suggests that applying topical Tempol to the scalp before whole brain radiation may protect against radiation-induced alopecia and is safe and well-tolerated.
990 citations
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October 1999 in “Development” This study found that LEF1/TCF3 is necessary but not sufficient for TOPGAL activation in hair follicle development, indicating complex regulation in the skin.
January 2025 in “Termometer Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran” In this study, researchers tested a tea leaf ethanol extract (Camellia sinensis) hair tonic and found it increased average hair growth compared to positive and negative controls over 28 days, but exhibited some instability and inhomogeneity after accelerated testing.