Efficacy and Safety of Topical Tofacitinib for the Treatment of Alopecia Areata

    Siddhi Chikhalkar, Swati Prasanna, Tejas Vishwanath
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    TLDR Topical tofacitinib is effective and safe for treating alopecia areata.
    This study on the efficacy and safety of a 2% topical tofacitinib ointment for treating alopecia areata (AA) in 30 patients over six months showed significant hair regrowth and reduced disease activity, with 40% of patients exhibiting an excellent response. No adverse events were reported, indicating the treatment is well-tolerated. However, the small sample size and short follow-up period are limitations, and further research is needed to confirm these findings and optimize the formulation.
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