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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

New treatments targeting T-cell pathways are needed for better alopecia areata management.

Melanocytes are important for skin and hair color and protect the skin from UV damage.

Different proteins are linked to the varying thickness of sheep and goat hair types.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

miR-140-5p in certain cell vesicles helps hair growth by boosting cell proliferation.

Use telemedicine and strict hygiene for safe hair and scalp treatments during COVID-19.

The research found that certain microRNAs are important for human hair growth and health.

DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.

The endocannabinoid system affects oil production and inflammation in skin cells.

Zinc deficiency disrupts hair growth and cycle, but zinc supplements can fix this.

Dermal stem cells help regenerate hair follicles and heal skin wounds.

Testosterone increases heart and blood pressure issues in rats with endotoxemia, and stopping testosterone production can reduce these problems.

MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

Low-dose naltrexone might be a cheap and effective additional treatment for hair loss with scalp discomfort due to its anti-inflammatory effects and few side effects.

Hydrogel scaffolds can help wounds heal better and grow hair.

IL-3 worsens lupus nephritis and blocking it improves kidney health.

Two mutations in KRT74 and EDAR genes cause sheep to have finer wool.

Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.

New treatments for hair loss from alopecia areata may include targeting immune cells, using stem cells, balancing gut bacteria, applying fatty acids, and using JAK inhibitors.

Heat Shock Proteins are important in the development of Polycystic Ovarian Syndrome and could be targets for new treatments.

Eating apples can help prevent heart disease, cancer, and other conditions because they have healthy plant chemicals.

Forsythiasides have multiple health benefits but may cause pseudoallergic reactions, and more research is needed.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.