January 2025 in “Multimedialen Archiv und Publikationsserver der Christian-Albrechts-Universität zu Kiel (Christian-Albrechts-Universität zu Kiel)” In this study, human gingival mesenchymal stem cells responded differently to inflammation mediated by oxidized low-density lipoprotein (oxLDL) compared to cytokines; oxLDL significantly reduced cell proliferation but had less negative impact on differentiation characteristics.
January 2022 in “Dermatology Review” This study found that patients with chronic kidney disease-associated pruritus had elevated serum levels of interleukin 31, suggesting a possible role of this cytokine in the condition.
105 citations
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September 1995 in “Journal of The American Academy of Dermatology” This review discusses the use of recombinant cytokines as therapeutic agents in clinical settings and describes the range of cutaneous complications associated with their use, including both minor and severe skin reactions.
September 2016 in “Elsevier eBooks” Different types of hair loss in dogs and cats have various causes and treatments, with outcomes ranging from good to uncertain.
38 citations
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January 2017 in “Mediators of Inflammation” This study found that platelet-rich growth factor significantly reduced the release of proinflammatory cytokines in an in vitro rheumatoid arthritis model.
7 citations
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August 2024 in “Journal of Functional Biomaterials” This review concludes that platelet-rich plasma injections significantly improve knee joint function compared to alternative treatments in managing knee osteoarthritis.
3 citations
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May 2015 in “Journal of archives in military medicine” This review discusses the regenerative potential of platelet-rich plasma in military medicine applications, finding inconsistent but generally favorable outcomes across various conditions, including tendon and bone injuries.
1 citations
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March 2018 in “Hair transplant forum international” This article reviews regenerative therapy for treating various types of hair loss and does not present new clinical findings.
32 citations
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April 2017 in “Scientific Reports” This study found that 5% activated platelet-rich plasma significantly improved cell proliferation and hair-inductive ability of dermal papilla cells in vitro, and promoted hair follicle formation in mice.
3 citations
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January 2021 This chapter explains the mechanisms of facial aging and evaluates non-surgical treatments like thread lifts, platelet concentrates, high intensity focused ultrasound, and radio frequency for addressing aging signs, highlighting their potential for excellent patient outcomes.
December 2025 in “Cell Communication and Signaling” This study discovered that minoxidil affects hematopoiesis by downregulating wnt4, leading to suppression of hematopoietic stem and progenitor cells and alleviating MDS-like symptoms in zebrafish and mice, with hematologic safety achieved at optimized doses.
5 citations
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February 2022 in “International Journal of Molecular Sciences” This review discusses the roles of distinct immune cell types in skin wound healing, highlighting findings from animal studies, but provides no new clinical results.
4 citations
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January 2019 in “PubMed” This study found that low dose valproate monotherapy in epileptic children commonly leads to side-effects like weight gain and decreased appetite, especially among younger patients.
November 2025 in “International Journal of Molecular Sciences” This review covers the diverse clinical applications of platelet-rich plasma in regenerative medicine but provides no new clinical results.
3 citations
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December 2021 in “IntechOpen eBooks” This article reviews the potential of bionanomaterials, derived from natural biomolecules, for wound healing and reports no new clinical results; it emphasizes the need for further research in this area.
21 citations
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March 2023 in “Journal of Crohn s and Colitis” This study suggests that microvascular damage and platelet deregulation may persist in ulcerative colitis patients even during remission, remaining as disease-associated molecular signatures.
13 citations
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January 2017 in “Annals of dermatology/Annals of Dermatology” In this study, simvastatin/ezetimibe treatment led to partial hair regrowth in about 29% of patients with recalcitrant alopecia areata, suggesting it may be a viable alternative therapy for this condition.
2 citations
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November 2025 in “Biomedicines” This review explores how platelet- and marrow-derived biologics like PRP and BMAC exhibit both regenerative and antimicrobial properties useful in musculoskeletal conditions and wound healing, though their clinical outcomes are affected by preparation inconsistencies and lack of standardized protocols.
June 2026 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This review highlights that various components of "skin boosters," such as exosomes and hyaluronic acid, may have potential applications beyond aesthetics, acting as adjunct therapies for improving skin integrity and promoting tissue regeneration, though more research is needed to support their use as primary treatments.
October 2025 in “Skin Health and Disease” This review found preliminary evidence suggesting that photothermal conditioning enhances the bioactivity of platelet-rich plasma, potentially improving hair regeneration outcomes, but highlights the need for standardized protocols and further studies to confirm its efficacy and safety.
October 2025 in “Lasers in Medical Science”
April 2025 in “Diagnostics” This review synthesizes data suggesting that managing inflammation and oxidative stress may enhance the effectiveness of PRP therapy for hair regeneration, though standardizing PRP protocols remains challenging.
October 2023 in “Pediatric dermatology” This study found that Middle Eastern patients with epidermolysis bullosa show specific correlations between their genetic variants and clinical features, which may aid in diagnosis and genetic counseling.
169 citations
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October 2020 in “Pharmaceutics” This review discusses recent advancements in formulating electrospun nanofibers as wound dressings, emphasizing their advantages in incorporating bioagents for improved healing, but reports no new clinical results.
15 citations
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April 2016 in “Medicine” This study reports that systemic lupus erythematosus patients with Evans syndrome often exhibited photosensitivity, hypocomplementemia, and elevated serum IgG, while lupus nephritis was less common, suggesting distinct clinical features.
4 citations
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August 2023 in “Frontiers in Pediatrics” This study observed that children with multisystem inflammatory syndrome associated with COVID-19 exhibited physical intolerance and fatigue shortly after the acute phase, but significant improvements in exercise capacity, laboratory markers, and cardiac health were reported by six months post-discharge.
1 citations
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December 2023 in “Life” This article discusses the potential role of telocytes in skin regeneration and the need to understand their interaction with platelet-rich plasma, reporting no new experimental results.
March 2026 in “IntechOpen eBooks” This chapter explores the promising use of low-power laser irradiation for post-hysterectomy reconstructive care, emphasizing enhancements like a flexible fiber optic module, to potentially improve genitourinary rehabilitation in cervical cancer patients.
July 2024 in “Anais Brasileiros de Dermatologia” PRP injections can increase hair density in people with androgenic alopecia.
April 2023 in “American Journal of Transplantation” This study found that hormone replacement therapy was associated with reduced COVID-19 mortality and adverse outcomes in nonimmunosuppressed postmenopausal women and immunocompromised male solid organ transplant recipients.