Minoxidil Ameliorates Myelodysplastic Syndrome by Targeting Wnt4 While Sparing Normal Hematopoiesis

    December 2025 in “ Cell Communication and Signaling ”
    Xiaoling Shi, Yushi Liu, L Huang … Lin Qing
    Studysummary This study discovered that minoxidil affects hematopoiesis by downregulating wnt4, leading to suppression of hematopoietic stem and progenitor cells and alleviating MDS-like symptoms in zebrafish and mice, with hematologic safety achieved at optimized doses.
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    Research cited in this study 12

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