Systemic Minoxidil Accidental Exposure in a Pediatric Population: A Case Series Study of Cutaneous and Systemic Side Effects

September 2021 in “ Journal of Clinical Medicine ”

Manuel Sánchez‐Díaz, David López‐Delgado, Trinidad Montero‐Vílchez, Luis Salvador‐Rodríguez, Alejandro Molina‐Leyva, Jesús Tercedor‐Sánchez, Salvador Arias‐Santiago

TLDR High-dose oral minoxidil in children can cause increased hair growth, especially on the face.

This study investigated the side effects of high-dose oral minoxidil in a pediatric population due to accidental exposure from contaminated omeprazole. It involved 20 patients aged 2 months to 13 years, who received an average dose of 0.90 mg/kg/day over 38.3 days. Hypertrichosis was observed in 65% of the patients, typically appearing after 24.31 days, with the face being the most common initial site. Systemic effects were noted in 15% of the cases, but no severe disorders were reported. The study provided new insights into the side effects of high doses of oral minoxidil in children.

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Research cited in this study

19 / 19 results

research Low-Dose Oral Minoxidil Improves Global Hair Density and Length in Children with Loose Anagen Hair Syndrome

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Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.

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Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

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Minoxidil helps lower high blood pressure in kids, but can cause fluid retention and hair growth.

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Minoxidil-Induced Hypertrichosis in a Child with Alopecia Areata

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